ysco

Generalized lymph node swelling is usually less worrisome than a localized but nonproportional lymph node swelling. The first often indicates an infection, the latter may indicate something more serious such as cancer. But that's variable anyway.

As Greeneyesofblue mentioned, apparently in some people the reactive (post-infection) nodes tend to stay enlarged even after the infection has cleared. In most people the nodes do decrease in size over time until they reach their original size, but it's not unusual for reactive nodes to take several months to withdraw back to their normal size. And in some (probably uncommon, but existent case), they never withdraw at all.

You did not mention how your nodes feel, how big their are, etc.. Do they all feel about the sime? Are some nodes remarkably larger than others? Do some nodes continue to grow?

The most important and distinguishing thing about lymphadenopathy is whether the associated nodes enlarge in a pattern or sporadically. For instance, the most worrisome factor is when some node(s) grow out of proportion to the other nodes, AND continue to get bigger. This may imply on a malignant process. This in contrary to reactive nodes that usually (though not always, depends what type of infection causes them and how severe it is) enlarge in a certain pattern and subsequently withdraw to their normal size.

Also, your systematic symptoms (particularly night sweats) are worrisome in a way but may be related to some persistent infection (e.g. bacterial or viral) you're suffering from, and you may not even be aware. Perhaps even anxiety plays a roll.

I would suggest you continue your followup with your doctors. Or see others if you don't find your current ones helpful and continue to worry. If you got abnormally larger nodes, it wouldn't be a bad idea to have one of them biopsied, just to be sure everything is alright.

Hope this helps.