Re: hormone treatment
I think being involved in a research study is kind of like being a guinea pig. I wouldn't do it. This stuff hasn't been tested on anyone yet, so you don't know what could happen. The other issue is that you may end up part of the control group; that is, usually there is always a control group. Being in the control group will mean you are most likely receiving just a placebo. That means you may not be getting anything for your symptoms. Again, kind of like a guinea pig because you don't get any kind of treatment during that time in the research project, if you are in the control group.
The one book I would highly recommend is by John Lee MD. He wrote several on the subject, including ones on menapause and peri-menapause. His books have excellent information in them. Lee pioneered the use of natural progesterone cream. If you are really serious about understanding hormones and specificially bio-identical hormones, then you should consider Lee's books. You could probably find some other information on his books and his recomendations on the internet too. Good luck.