Originally Posted by armadillo pie
It apears that estrogen and progesterone symptoms overlap. Tender breasts seem to both a symptom of both! So I am back to square one. Anyone out there have any personal experience with this?
Yes, I do. With estrogen dominance, you can have soar breasts and you can have soar breasts with progesterone too. But to have progesterone dominance, the only symptoms you are going to feel are moodiness, exhaustion or fatigue and depression. And these can come with estrogen dominance too. I doubt you would be progesterone dominance cause if you are in perimenopause, you would have lost most of your progesterone. Progesterone is produced during ovulation only. When you first begin to feel ovulatory failure, you still have progesterone produced in your body in what we call store areas. But progesterone overload really isn't dangerous, it's the estrogen dominance that can be by causing fibrocystic breasts, uterine fibroids, cysts, headaches, heavy periods, even light periods, body aches, anxiety, etc. If you are in your late 30's or in your 40's, even 50's and still ovulating a bit or even not at all, you would still be estrogen dominance cause estogen is stored in fat, it's also stored in brain, nervous system, breasts, stomach, bladder and adrenaline glands, so is testerone in the adrenaline glands. Your adrenaline glands produce progesterone also and this is why they kick into women so hard and they have anxiety cause the adrenaline glands are producing hormone that your ovaries are not any longer. Now, everytime you get a period, you are setting new estrogen set points. So let's say you don't have a period for awhile and then you get all of sudden, the body goes through setting new estrogen points so this might make you feel out of whack again because of this. I know it's a roller coaster and I know it's difficult to understand but I would say perimenopause is definitley a very serious hormonal inbalance. To do natural progesterone creme will not harm you, but you need to have an alternative or naturopathic doctor watch you on this, since you will need to be regulated. Even Chiropracter's and gyne's who practice alternative medicine will do this for you. I hope this helps or if you have any further questions, we can go from here.