I am postmenopausal (57 years old) and have extreme vaginal dryness which I have very painful sex and some bleeding after sex. I'm married and this is a BIG problem for my marriage. My husband is fit to be tied as we have not been able to have intercourse for 2 years. I've had the various tests to make sure I don't have uterine cancer, etc. I want so much to be able to have intercourse. I didn't want to take HRT because of all the risks associated with it; and opted to take Vagifem. I did research and it appears to be relatively safe; however there is risk associated with this as well. I just started the drug and the 1st day I had spotting, which is scary! I just left a message for my doctor. Just curious, has anyone taking Vagifem had spotting occur right away? Or, perhaps you've had success with this drug. I'd love to hear either way how it's going for you. Perhaps you have found other remedies that have worked. I've tried the many OTC lubricants, gels, suppositories to no avail. Thanks for your help.