Originally Posted by JinL
I think it was about a month to lower it. I took 2 DIM & 1/2 Arimidex 3 times a week. The day of my "T" injections.
You do not want the E2 to be below 10 as that can cause problems.
I'm late finding this thread but I'm quite glad I did. I'm very curious to know more about your response to Arimidex. My situation is as follows:
About 5 years ago I fell very ill. Took me 5 years of hell to figure out my hormones were messed up. Last January I had saliva labs done showing shot adrenals (flatlined), and a very sluggish thyroid with a screaming TSH. Since going on HC and Thyroid for these, I feel much better... but still only about 50%. I thought it may be a pituitary issue but my thinking now is that it may all be caused by significant estrogen dominance:
January saliva readings:
E2 (Estradiol) - 5 - Ref. Male (20-49 yrs): 1-3 pg/ml
P1 (Progesterone) - 27 - Ref: Male (adult): 5-95 pg/ml
TTF (Free Testosterone) - 22 - Ref. Male (20-30 yrs): 60-110pg/ml
... keep in mind it is saliva but blood tests have confirmed the same findings. I have a high total T, but very low bioavailable and free T. Add to that high E2 and SHBG and I think I may have found out what's going on... the estrogen is totally slowing my system.
I'm only 26 and weigh 180 pounds. I look slim but it's all fat... no muscle... no sex drive... it's horrible. I had a run in with drugs, poor lifestyle, and then came out of it... but I think my T/E ratio got all messed up.
So I have Arimidex on the way. I have done the Indoplex w/ DIM and it worked for a brief stint. I was getting erections and felt slightly better. But then it was gone... I was doing a lot of it too. Combined with zinc even. Even came off of it for weeks to see if I had driven E too low - clearly that was not the case however.
I am so tired all of the time, I don't get good sleeps, no sex drive, my testicles are rather small. Lots of body fat despite a small frame (strange really). Overall I feel very sluggish... stressed too.
I'm wondering what you noticed - in detail if you can, from taking Arimidex? And based off what I mentioned above, does it sound like I would see a good benefit from taking it?
I know the temper in going overboard. Currently though, with the DIM I am not even close to getting anywhere with my E problem (I feel). It's funny, but I was going to use a very similar strategy to you - taking DIM with the Arimidex. (ie. DIM metabolizes the E making way for T, and the Arimidex will ensure the new T stays T).
What sort of benefits (mind & body) did you see Jin? I'm super curious in anticipation. I think I've stumbled upon what could make me feel a lot better - and could improve my other hormones, namingly cortisol and thyroid.