Re: Lowering E2 - DIM vs. Arimidex
I just found an interesting study in The Journal of Endocrinology and Metabolism, titled " Effects of Aromatase Inhibition in Eldery Men with Low or Boderline-Low Serum Testosterone Levels".
It was a 12 week study of 37 men with an average age of 67, split into 3 groups. Group 1 was given 1mg of Arimidex a day, Group 2 was given 1mg of Arimidex 2X per week and Group 3 was given a placebo. There was no TRT involved. After 12 weeks there was little change in the placebo group for any measured parameters. E2 levels decreased 35% for Group 1 and 37% for Group 2. Bioavailable T increased 109% for Group 1 and 55% for Group 2. Total T increased 67% for Group 1 and 31% for Group 2. LH increased 55% for Group 1 and 75% for Group 2. PSA increased 6% in Group 1 and 29% in Group 2, but the Group 2 increase was because of a larger increase in 2 of the 11 men in that group.
I realize that these doses of Arimidex are higher than what is normally recommended for men using TRT, but it is interesting that the T and LH levels rose so much when on Arimidex. The ratio of total T in ng/dl to E2 in pg/ml rose from 13 to 34 for Group 1 and from 15 to 31 for Group 2.
Last edited by whytry; 07-28-2008 at 11:16 AM.
Reason: Group number and spelling