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Old 02-07-2009, 07:44 AM   #16
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Re: Just go my test numbers back

Quote:
Originally Posted by hayfarmer View Post
There is no way to know if you can restart you HPTA or not until you try. But it is definitely worth trying since hormone replacement at it's best will not make you feel as well as you did before all this started....plus it's just generally a pain in the a**. See if this new endo will let you try the clomid test where you take clomid for a few weeks and then test for LH and T to see if they responded at all. You must be off the androgel during this test. If your doctor(s) will not give it a try you may have to travel to Dr Shippen or Dr. Crisler. You really should run all the tests too after being off androgel for a couple weeks to make sure there is not something else obvious causing this. Those tests should include total T, LH, FSH, TSH, prolactin, total estrogen, estradiol at a minimum.
Hayfarmer...thanks for the thoughts

here were my numbers from last test...this was being on Androgel for about 60 days at 5mg/day

Total T 318
Free T 7.9
Estradiol 17
Cortisol 11
FSH 1.0
LH 1.1
Prolactin 2.7
DHEA 1.7

I will suggest the clomid test to him....really hate however to be off of any replacement therapy as the side effects really suck.

Was hoping that he would place me on HGC therapy with some T and see what happens.

Have you heard if Nebido is availabe in US yet...if one has to stay on T it sound great.

Lou

 
Old 02-08-2009, 02:22 AM   #17
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Re: Just go my test numbers back

Quote:
Originally Posted by boscogto View Post
Cortisol 11
FSH 1.0
LH 1.1
Prolactin 2.7
DHEA 1.7
What were the normal ranges for these hormones? If these were taken at 8am then it appears your cortisol and DHEA are on the low side. Combined with low FSH and LH, that's a sign of pituitary problems. You should probably have a MRI to rule out a pituitary tumor and a stimulation test to verify that your growth hormone is low as well. You should have blood tests for TSH, T3 and T4 to determine the state of your thyroid as well as a blood test for ACTH the hormone that activates cortisol.

Signs of low cortisol may include, low blood pressure, dizzy spells, night sweats, morning backache and loose diahrea like stool along with stomach and gut upset (similar to Crohn's disease symptoms).

PS: was DHEA tested or DHEAS? because DHEA is a worthless test since it remains in the blood for a very short time, DHEAS is the long term form of DHEA.

Last edited by orion; 02-08-2009 at 02:25 AM.

 
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Old 02-09-2009, 07:18 AM   #18
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Re: Just go my test numbers back

Orion

don't have all the numbers from past as known were taken. Only number recieved prior to getting any supplmental T was the original 308 total T number. Dr. is assuming that since my numbers didn't change at all with the supplemental T, went from 307 to 318, that the other numbers most likely didn't change either....so he feels its safe to say what they are now is what they were prior to starting.

I was checked for Thyroid problems but to my knowledge never pituitary issues. that is a interesting thought.

I will bring it forward to both my normal Dr. and the Endo I am going to see.

What can be done for a pituitary issue? Is it correctable? Treatable?

Lou

 
Old 02-09-2009, 11:31 PM   #19
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Re: Just go my test numbers back

Quote:
Originally Posted by boscogto View Post
What can be done for a pituitary issue? Is it correctable? Treatable?
Treatment depends on the cause of the pituitary problem and can be drugs, radiation, surgery or a combination. If in fact your pituitary is damaged then low cortisol can be life threatening in the case of sudden shock such as an accident or high fever. You need to rule out the pituitary fairly soon because lack of treatment can lead to permanent damage.

You should always get copies of your blood tests and keep a record for yourself because each lab has its own set of standards and without knowing the standards the tests are not as useful.

 
Old 02-10-2009, 07:15 AM   #20
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Re: Just go my test numbers back

Orion

thanks for the possible cause and info...I will discuss it with my endo next week. The question is did my Chron's cause this issue (my dr. thinks so) or is it a parella issue such as a pituitary issue. Not sure but both came on me slowly over the last 2+ years...and both got progressivelly worse together...both came to a head this fall. Treatment for Chron's has shown progress.... TRT has helped some of the symptoms but not all of my problems on other end.

 
Old 02-10-2009, 05:14 PM   #21
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Re: Just go my test numbers back

Quote:
Originally Posted by boscogto View Post
The question is did my Chron's cause this issue (my dr. thinks so) or is it a parella issue such as a pituitary issue.
I should have mentioned that there is plenty of evidence that low DHEA is associated with Crohn's and low DHEA can be caused by the pituitary. Likewise, low testosterone is associated with Crohn's and may be a contributing factor. It seems unlikely that Crohn's would be the cause of low testosterone since the origin of testosterone is the testicles interaction with the pituitary; so the converse seems more likely.

I would suggest you start taking probiotics with at least three different bacteria types as well as DHEA, starting at say 10mg/day and working up to 25mg/day. The probiotics should help with Crohn's anyway but always are good for digestive upsets. The DHEA may help put a damper on Crohn's progression.

Here is a medical journal article you can refer your doctor to:

Aliment Pharmacol Ther. 2003 Feb;17(3):409-14."Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study." Andus T, etal. Department of Internal Medicine I, University of Regensburg, Regensburg, Germany.

also,

Clin Exp Rheumatol. 1998 Sep-Oct;16(5):579-82. "Blood and tissue dehydroepiandrosterone sulphate levels and their relationship to chronic inflammatory bowel disease." de la Torre B, etal. Division of Psychosocial Factors and Health, Karolinska Institute, Stockholm, Sweden.

"CONCLUSION: These data indicate that low blood DHEAS is a feature in a majority of patients with UC or Crohn's disease."

 
Old 02-18-2009, 11:09 AM   #22
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Re: Just go my test numbers back

Well

met with the new Endo...looked at all numbers...had a very good case for it not being Pituitary. Felt strongly it was chronic illness related combined with Stress...that said if both were controlled he felt I should be able to restart the system.

So as Hayfarmer suggested...I am going off TRT and trying Comid therapy.

Dr. said it would 3-6 weeks prior to feeling much...wants to test me in about 6 weeks and see where levels are at.

Really hoping this might work...Dr. feels there is a good chance as I am otherwise is great shape with no other health issues.

Anyone had any success with comid???

Lou

 
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