Does anyone have experience with testosterone replacement?
My total testosterone has been decreasing over the last 3 years (from 622 to 450 now). I have been complaining about decreased libido, semen volume, and difficulty ejaculating for those last several years. My FSH is off the charts (30), but that's another subject...
Even though my testosterone is not technically low, my doctor wants to put me on topical testosterone since I'm having symptoms.
I asked about the risks--high RBC count, heart attach, stroke, shrinking testicles...He doesn't seem too concerned. But, I'm a little freaked out.
I wonder whether it makes sense to start this therapy at 42 since I'll have to be on it the rest of my life, but I really want to get back to having a reasonable sex life...What's a man to do?
I'd be interested in hearing from someone who is on T replacement--what are the upsides and downsides?
Try this forum and look for post by an individual name Ksman. He is an engineer who is interested in this topic.
450 might be great for some but everyone if different. Once person will function good at 450 and another wont. Your norm may be 600, 800+.
Basically to prevent highs an lows you inject yourself with testosterone twice a week like Sundays and Thursdays. My Dr suggested doing it in the mornings as it might give me energy. I have done mornings and evenings and I didnt notice a difference. Inject yourself in upper outer area of your vastus lateralis at home using something like a 27 gauge 1/2" insulin syringe. Yes it will take about 2 mins to fill the syringe but its painless!
You should be using a dose strength of 200mg/100ml for the following. You have your baseline so now, start with a dose like .25mg with each injection which will equal very closely mimic the amount the human body excretes each week. Im not sure what your estrogen (E2) is but its majorly important to find out before you begin. You need a baseline for that as well. Taking in more Test will make E2 go up so an anti estrogen like Arimidex is almost always necessary. You can find a legal liquid form on the internet. My Dr even approved of it. The test will shut down your testicles so to bring them back you need HCG! My Dr prescribed it but is reluctant that I need it long term. Really as long as your on Test you need it. With your testiciles shut down your DHEA is also cut off.
So you need to make sure you have ALL blood test done for a baseline. You need two scripts: Testosterone, and HCG. and you can buy a bottle of liquid Arimidex for about $60 and it will last a year.
Me personally, I found out that 0.23mg twice a week and 2 drops of Arimidex under my tongue a night put my testosterone at about 800 and my estrogen at 22.
Ksman is the man when it comes to this. There are also a few other on there that are good to. Just post your results and they will help you out. Be sure to read some of the articles on there first.
Hope this helps.
Last edited by moderator2; 06-06-2010 at 09:53 AM.
Reason: please do not post websites except as described in the Posting Policy
Well, I'm not getting the kind of response I was hoping for here, so I thought maybe I'll blog about my experience to be a resource for others.
Testosterone cream arrived yesterday (not Androgel-this came from a local compounding pharmacy). Took first dose this morning (100 mg). Opted to spread the cream on the inner sides of both forearms. Blood vessels became noticeably distended, but that was it.
I'm feeling hopeful and somewhat anxious. Hopeful that my libido and erections of 10 years ago will return. Anxious about the potential side effects. But comforting myself with the thought that this is a pretty low dosage (I think).
I tried it but didnt like the side effects:
Testicular shrinkage, acne, gynecomastia(breast enlargement) It did improve libido and ED plus strength and sense of well-being. I have since learned about the problem of testosterone aromatizing into estradiol which causes the gynecomastia. There are things you can take to counter that but my local docs including my endo aren't up on that. Sad situation they give you male hormone because your output is low and it destroys your maleness.
It's important to understand that there is usual more than one factor involved in hormone imbalance. TRT alone is not necessarily going to provide the answer. That's why it's so important to consult an endocrinologist who is both willing and able to deal with your case. It's worth looking for one that specialises in andrology - male hormonal problems.
Yes... the cream will help at first... But the test will get converted to estrogen as your body tries to stay in its current balance or ratio of test/estrogen. The cream can cause irritation after a while and the body gets to where it doesn't absorb it as well after a while also. Your body will never have problen with injections and there easy and painless with a small needle.
You need 3 things: Test, anti estrogen, and HCG
Test injected IM into your vastus lateralis with a 27 gauge 1/2" needle or SubQ 1"-2" from your belly button in any direction. Do that twice a week in the mornings spread apart like on Sunday and Thursdays.
Then you need an anti estrogen. Liquid Arimidex can be bought legally on the internet as a research chemical. I ran it across my dr. first and he said it was ok... You should start with 3 drops under your tongue a day or you can do them all at once on any day of the week since the half life will keep it in your system all week.
The HCG which your dr. might not be willing to Rx... will restore your testicles to normal. THe test will shut them down but the HCG will reverse it. Plus your DHEA production is cut off when there shut down. HCG turns that back on to.
Drs usually like to give 200mg every two weeks which will make you feel great and then like crap!! If you split that up and take 50mg twice a week you mimic the bodies natural production better. Plus you can do it at home! Then the 3 drops of Arimidex a day, along with I think (its late)... 250mg every other day of HCG SubQ in your stomach will or should put your test at 600-900 and your estrogen at 20ish...
It takes about 5 weeks for all this to level out (for lack of a better way to say it). Then get another blood test and adjust it all the test and Arimidex.
If you Google some of this you will find many people who have done this protocol with great success. Study up on it. Print off research that you find to back it up. go to your doctor and be honest and open with him and what you are trying to accomplish. Hopefully he will see and help you out.
Although it is legal to buy it as a "research chemical", it is not intended for human consumption or "self prescribing". It is meant to be used for research (aka rats, etc) since human use requires a prescription by law.
I would not publish this kind of advice on a public forum.
Just as sominex and benadryl are the same drug, liquid Arimidex (Anastrozole) bought without a prescription is the same thing as the tablets you get with a prescription. It's pretty hard to take a 1 mg tablet and split it 7 times!!! Plus around $60 a year for the liquid verse what my original prescription was going to cost $400+ for 30 days!!! Ouch!! But as I was starting all this and researching it, I showed the ad from the net to my doctor for liquid Arimidex and even he said it sounded like a better thing to do. He said it would mimic the bodies natural secretions better. Then he wanted to get some himself to try with other patients. It's perfectly legal!! and if you google it, there are dozens of websites or more where thousands of people do exactly what I mentioned above with no problems.
My natural estrogen was 60 and my Test was around 250!! Now my estrogen is around 20-25 and my test hovers between 700-800. I sleep 3-5 hours a night and I have tons of energy... ALL the time... I run sprints just to stay calm!! even with getting 3 hours sleep most nights studying for nursing school! I feel like superman!! I have always worked out some, but I actually see results now!!! I'm like a normal guy for once! Plus instead of wanting sex once a week or less... I want it everyday. I feel like I could run 100 miles and make love for hours! You can get that by keeping your hormones in balance!! Funny how hormones do all that. But just about everybody who uses test with out an anti estrogen will see there estrogen go sky high putting them at risk for a stroke and making erections a thing of the past. Whats posted above, is good advice and it helped me and lots of other people. Matter fact because of this, is the reason I went back to nursing school. I have degrees in exercise physiology and nutrition so I was already interested in the medical field anyway. The thing is... no matter how good I got someone to eat or workout it could never match just getting the hormones in balance. My physician has a nurse practitioner who specializes in womens hormones that works with him. I hope to do the same thing but also target men. I remember being forgetful and tired all the time. I feel awesome now and I don't forget things all the time anymore. I want to be able to work with people and help them the way my physician helped me. I have a long way to go... I wont post on this anymore as I need to study... Allll weekend unfortunately!! But this WILL work! Google it... research it... study it all out... know your stuff and then go have a chat with your physician. Good luck!