Hi Betsy,
I have my 8th one tomorrow and what I can tell you is to start taking Motrin or Tylenol about 2 to 3 hours before your shot and you can alternate between the two if you wish to keep it in your system. I also take the shot towards the evening so I can sleep through most of the side effects. My first time I had chills, low fever, & aches simular to the flu, but since then this has decreased greatly to just a low fever and slight joint discomfort. I have heard others say to drink plenty of fluids throughout the day as well (I haven't tried this yet). Plus either set out the syringe or I just hold it in my hand for about 5 to 10 minutes to warm it up. Good Luck and let us know how it goes.
It does get easier through time, just gives us a new meaning to T.G.I.F.
Take Care,
Dave