I'm very curious to know what else can cause spots on the brain??? From all my research I have only found that Lymes Disease can put Spots on the brain. Please post what else can put spots on the brain. I have 8 spots on my brain (that they could see), Im having a Spinal Tap Friday. Doctor is leaning towards MS, but if there is something else that can put lesions on the brain, I would love to know what it is. Thanks,,,,please let me know..