I have been on Betaseron for over a year. I had a few times where I felt a sting, but that was before using the Auto-Injector. Are you using it? I also take Tylenol a half hour before the shot and use an ice pack 5 minutes before the shot, it seem to work. I too have spots. I have learned that they don't go away quickly at first but over time your body will get used to it. I do most of my shots on my stomach and butt area (I have more cushion there
). 10 days afte I started Betaseron I got progressively better. I was recovering from my first and very severe attack.
Hope this helps!