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Old 05-12-2007, 03:52 PM   #1
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Any Bloodwork Point To Ms?

Just wondering if anything shows in bloodwork of MS patients. I know there isn't a bloodtest for it but are there any abnormalities that may show in MS?

 
Old 05-12-2007, 03:59 PM   #2
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Re: Any Bloodwork Point To Ms?

Hi, kdel. The only thing I'm certain about is that there isn't any blood work to confirm it. However, I believe there are things that could give reason to be more suspicious that it might be MS. I don't know what those things are but my neurologist/MS specialist told me that depending upon what blood workup my primary care doc ordered, he might ask for additional testing. He didn't have to so apparently everything was covered the first time but I don't know what tests he was looking for. Very good question though and I'll be asking next visit! In the meantime, hopefully someone else can fill us in!

 
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Old 05-12-2007, 07:27 PM   #3
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Re: Any Bloodwork Point To Ms?

Most Dr's do blood work to rule out other disorders.

When they do a LP or spinal tap they do blood work to compare the spinal fluids and blood.looking for O-bands,proteins.

 
Old 05-12-2007, 07:41 PM   #4
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Re: Any Bloodwork Point To Ms?

I knew they ruled things out by blood work but my doc asked this after I was already diagnosed. It's definitely possible that's the extent of it but that's why kdel's query gave me another question to put on my list!

 
Old 05-13-2007, 04:09 AM   #5
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Re: Any Bloodwork Point To Ms?

Quote:
Originally Posted by nuffs3 View Post
Most Dr's do blood work to rule out other disorders.

When they do a LP or spinal tap they do blood work to compare the spinal fluids and blood.looking for O-bands,proteins.
So, does that mean you would have abnormal protiens in your bloodwork? If so do you know which ones? I have some protiens that are present and also bands called igm, kappa, and lambda. This may as well be another language to me! Are obands just called obands and are they only in spinal fluid? I have had alot of bloodwork done but no spinal tap or recent mri yet. Thanks.

 
Old 05-13-2007, 01:53 PM   #6
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Re: Any Bloodwork Point To Ms?

When they do the LP and blood work the O-bands stands for oligoclonal bands that can be present both in the blood and spinal fluid.Many neuro's consider 2 and under normal.They also check for myelin basic protein in the spinal fluid and the blood(some facilities don't check the MBP in the blood)
If the MBP is elevated or high it tells the DRs that the body is attacking the myelin sheath on the nerves consistant with MS and neuropathies.
They also check the albium ratio if that is high then the blood brain barrier is being broke through thus causing lesions.
There is a blood test that a DR at the Cleveland clinic done,well several ,this one came back abnormal (low 35--normal range 72-124)1-methylhistidine which is seen in parkinsons and MS.Many Drs don't run full muscle enzyme blood panals as they are very expensive.

 
Old 05-13-2007, 03:48 PM   #7
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Re: Any Bloodwork Point To Ms?

I have a silly question. If they can tell all this from blood work, why do they do the lumbar punctures? Do they only do LPs if the blood work shows a reason to do them?

 
Old 05-13-2007, 04:06 PM   #8
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Re: Any Bloodwork Point To Ms?

The spinal fluid needs to be compared to the blood serum.

Most Drs don't do LP's unless MRI's are inconclusive.

 
Old 05-14-2007, 04:28 AM   #9
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Re: Any Bloodwork Point To Ms?

True, but also, in certain parts of the country, where Lyme is really rampant- they are doing LPs allot more often. New studies show that Lyme tests via blood work are not 100% accurate, and an LP can give that 100% positive or negative dx of Lyme.
I live in the North East, just outside NYC, but in Central North Jersey, believe it or not, we have the most deer in the state, right here in my county. Over 3000 cases of Lyme are dx a year here in this county alone. When my doctor wanted to rule out Lyme, he didnt hesitate to start with an LP.

Its not that horrible, no where near as bad as my imagination thought it would be.

Nikki

 
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