changing trials - Multiple Sclerosis Message Board

mitch512u · 01-15-2008, 07:31 AM

Hi all.

Today is the day I am officially leaving the clinical trial I have been in for the past 2 1/2 yrs. That was the CombiRx trial. For those of you unfamiliar with this trial it is the one testing weither Avonex and Copaxone in combination work better than either alone. I have decided to leave this trial due to a major relapse a month or so ago. My neuro. felt that the treatment was not working for me and asked if I would consider a different trial. After a couple of weeks I decided that I would.

Today I am going in for my final MRI and other testing which will complete this study for me. Then it is 3 months off of all med's. Hopefully no relapses during this time. Upon the completion of the 3 month 'purge' I am to begin the trial for fingolimod. The trial last's 2 yrs. I have a one in three chance of recieving the 'real thing'. One either gets .5 mg or 1.25 mg or placebo once a day. Its administered orally...yay!

If any one is interested go to clinical trials .gov The identifier is: NCT00355134 The trial is still recruiting.

Mitch

cyprian1 · 01-15-2008, 07:39 AM

Quote:

Originally Posted by mitch512u

Hi all.

Today is the day I am officially leaving the clinical trial I have been in for the past 2 1/2 yrs. That was the CombiRx trial. For those of you unfamiliar with this trial it is the one testing weither Avonex and Copaxone in combination work better than either alone. I have decided to leave this trial due to a major relapse a month or so ago. My neuro. felt that the treatment was not working for me and asked if I would consider a different trial. After a couple of weeks I decided that I would.

Today I am going in for my final MRI and other testing which will complete this study for me. Then it is 3 months off of all med's. Hopefully no relapses during this time. Upon the completion of the 3 month 'purge' I am to begin the trial for fingolimod. The trial last's 2 yrs. I have a one in three chance of recieving the 'real thing'. One either gets .5 mg or 1.25 mg or placebo once a day. Its administered orally...yay!

If any one is interested go to clinical trials .gov The identifier is: NCT00355134 The trial is still recruiting.

Mitch

Mitch you are doing all of us a great service , being a guinea pig for trails has got to be frustrating .. i know i couldn't do it ... very proud of you .. God bless and good luck .. thanks again .. cyp1

MSNik · 01-15-2008, 08:05 AM

Hi Mitch. Bet your scared of the 'what ifs" arent you? I would be...but as Cyprian said, Thank you for being able to do this...Im not able to get on any of the trials which I have tried to get on, due to having had so many other, NON related MS issues recently....but I appreciate you and what you are doing.
I dont think you are going to relapse during the 3 month period...your too good a person to let that happen...but do what you can to stay strong- get lots of rest...stay hydrated and keep doing exactly what you have been doing and lets hear how it goes..
God bless you for all you are to us..
Nikki

duttin · 01-15-2008, 01:06 PM

Mitch,

Your An Inspiration To All Of Us.

I Can't Get Into A Trial Do To Arachnoiditis And Radiculopathy,nerve Diseases.

Keep Yourself Strong,eat Healthy,get Some Exercises And Plenty Of Rest.

A Friend Of Mine Locally Is Doing The Clinical Study You Have Been Doing.

You Guys Are Very Special To Us.

Keep Us Posted On Your Progress.

T

Bearygood · 01-15-2008, 02:27 PM

Aw, Mitch, I'm sorry it wasn't working for you. I wish you best of luck in the new trial and look forward to hearing about your progress! I hope you get the real thing and it works for you!