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Old 04-16-2008, 12:52 AM   #1
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Oral dmd

I have been reading about trails etc but has anybody here heard from Dr when these might be available.

 
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Old 04-16-2008, 02:23 AM   #2
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Re: Oral dmd

No idea, but I am very interested myself.
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Old 04-16-2008, 05:30 AM   #3
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Re: Oral dmd

Oral DMD has been pushed back for the 3rd time, now they are claiming fall of 2009....
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Old 04-16-2008, 05:47 AM   #4
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Re: Oral dmd

Quote:
Originally Posted by MSNik View Post
Oral DMD has been pushed back for the 3rd time, now they are claiming fall of 2009....
Is this for testing with humans, or have these already been tested/proven?

What is the history of oral DMDs?

I'd guess this would first be available in the USA, and eventually other countries?
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Old 04-16-2008, 10:49 AM   #5
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Re: Oral dmd

The different stages of approval for a drug are 3 stages, with stage 4 being after it is released, based on longer term results...at stage 3, it can be approved by the FDA for public release- and yes, at this point, it has been tested for as many as 15 years on humans...

FTY720 is the name of the oral drug...the academy of Neurology just published yet another study on it this week... this is being produced by Novartis pharmaceuticals.. the clinical trials are under the name Freedoms.

Another drug is being produced by Serano (the makers of Rebif) which is still in phase 2 trials- its being done under a study called Clarity. the drug is called Oral cladribine and in many states they are looking for volunteers now for the final stages of the study...they are pushing for a quick release of this drug once stage 3 is finalized, which should hopefully be in the next 18 months.

The biggest drawback at this time seems to be the side effects, including nausea, inflammation of the nasal passages, breathing difficulties, and/or reduction in heart rate. The drug companies are still trying to work these out.

Hope this helps !
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