When I was on Avonex, I did it at 2PM on Sundays. This allowed me to feel okay most of the day, and by the time side effects (muscle ache and soreness for me) were kicking in, I could go to bed. This time also allowed the effects to subside before I had to go to work the next day. I also took naproxen sodium (generic Aleve), drank lots of fluids, and avoided alcohol the day of injection. My theory about the alcohol is that it is a diuretic (sp?), thus it dehydrates you and makes the flu like symptoms worse.
My $.02,
Jason
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Thank you sir! May I have another?
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