The Tecfidera vs placebo had a better result than with the other oral meds, but as the main ingredient is associated with a risk of PML, your doctor should have done preliminary testing for you and also he should have a monitoring plan for you.
I read patient feedback (not a clinical trial result) and the complaints most often heard were nausea, hair loss, and depression. Known side effects from the use of Tecfidera can include flushing, abdominal pain, diarrhea and nausea.
MS diagnosed since October 3, 1982
MS onset circa 1977
Proud to be MED FREE!
Eternally blessed and eternally optimistic!<><
Tammy, the clinical trials for Tecfidera show a high rate of GI upset mostly in the first two months, followed by a high rate of lowered WBC (white blood count) - this is concerning to me, because it means you have less white blood cells to fight off infection. This, doesnt get better with time, whereas the GI upset does.
Hair loss, nausea, diarrhea and all the others are consistently reported.
The drug is brand new. There is no long term data on it. Its hard to say what they will find a year from now. In Europe they linked it to PML the brain infection linked to Tysabri. In the US, you have to be tested for JC VIrus, the virus also linked to PML. IF you have JC Virus, you can still take Tecfidera but its recommended that you have blood work every 6 weeks and MRIs twice a year.
Thats about all anyone knows at this point- again, its too new to know what the long term affects are. If you start it, please let us know how you are doing!