After trying Imuran, Prednisone, and Methotrexate, I still have Polymyositis flares due to increase CK levels and muscle inflammation. Doctors tell me it's time to taper off Prednisone, but my CK goes crazy with elevation.
Has anyone tried Rituximab for Polymyositis or Lupus? If so, were you involved in a clinical trial, or did your insurance company approve payment for this medication. How did the drug work for anyone who tried it?
Yes I Tried Rituximab and is working very good in my case all my cpk and ast liver coming down very good and fast in 2 months
How long did it take before you noticed improvement with Rituxan? I've had 2 infusions, the last being on July 1st, and the CK has dropped (I still take Prednisone), but the pain in the shoulders, arms, and back are still there.