I was on Cymbalta for almost four years.It worked very well in combination with Lyrica.To make a long story short.I take nine pills a day,it's so hard to tell if i have a new side effect.I had extreme sweating all day long,but never at nighttime.It was so bad I stopped wearing make-up,had to wear my hair up.My GP gave me a RX to stop the sweats thank goodness,a topical lotion.I've been OFF CYMBALTA for two months now & NO MORE SWEATS.I gained 60 lbs on all those meds.But now I wear make-up,a new hair-do,my self esteem is BACK.I'm ready to don my RED HAT again!