Ruby - I suffered mostly with the typical small fibre symptoms but going by an emg I also had some abnormal readings for the motor nerves as well.
I was able to slowly reduce my meds as the years went by as my neuro found the cause/s in the first lot of tests, it was prediabetes & low B12, which was addressed and led to the nerves to start repairing, now approx 6 years later on I am very lucky not to suffer with any nerve pain at all, they have fully regenerated, thank god & my neuro too
Dear Aussie, dont know if you remembered Cream78 writing about my problems with polyneuropathy (diagnosed by my neurologist after having a skin biopsy). Have been reading about Methylcohalamin 5mgs lozenges. Should I ask my neuro if it is safe to take these.
Hi cream9518, B12 methlycobalamin is very safe, there is no adverse side affects even in very high dosages, I believe the Japanese neuropathy experts treat some patients with as much as a whopping 40 mg a day.
Its best taken on an empty stomache for max absorbtion, I take mine just before I go to bed, It seems to have a relaxing affect on me but I know others that say it does the opposite giving them energy, everyone is differant.
B12 needs the other B's vitamins to work the best, so I would consider taken one tab of multi B at seperate time, if your low on B12 then 5 mg would be my choice for a few months then 1 mg per day should be enough to keep up a good storage.
Hello Aussie, weve talked before about meds, its so good to hear someone has recovered from sfn and were all very happy for you. In my case I still have not found the cause for my on going sfn in both the forefront of my feet. I'm going on about 8 years now and my neuropathy has not changed in the last few years, no worse but no better. I know to get any better I have to find the cause. My GP says I'm not diabetic and I dont drink but once in a great while now. My A1c and fasting glucose numbers all are ok. My last fasting glucose did come back at 95 which is the highest its ever been. I'm just wondering if I should see a specialist that deals with diabetes and let him test me, I dont have alot of faith in my GP. I was also wondering was your pre diabetes hard to diagnose and how did they finally arrive at the diagnosis. I'm starting to wonder if the meds ive been taking for years are contributing to the problem. I take 600mg of lyrica, oxycontin and norco, if its the meds I dont know what I will do because they are the only thing that makes my life somewhat normal. Just curious about your situation.
Hi captinsane1, an overnight fasting glucose test isn't a good test to rely on, in fact some full blown diabetics can have good fasting levels but once their system has been challenged with a 3 hour glucose tolerance test, it can show a complete differant story in some people.
My fasting levels were normal around 4.6 or 82.8 in the USA measurements, all the GP's I seen were telling me I didn't have any sign of diabetes but once I got to see my neuro he ordered the 3 hour GT test which showed up the prediabetes.
The A1c tests are pretty good at showing an average sugar level but don't show any occansional spikes in blood glucose that may happen.
As insulin resistance increases it makes the beta cells in the pancreas produce more insulin, so to completely rule out causation of a diabetic nature, It's wise to ask for insulin level testing whilst the Glucose tolerance test is being performed, a normal GP can order these tests.
If this turns out to be all clear then I would keep searching for other reasons why this is happening, a neuro that is neuropathy expert will know a lot more reasons and should test for them.
There are some drugs that can cause neuropathy but the ones you mentioned are not those ones.
best of luck to you
Aussie thank you so much for your response, its great to have someone on the board with your wealth of knowledge on the subject and I know the way you acquired it was the hard way, you lived it. While I'm picking your brain on the diabetes issue, let me ask you one more question.I'm going to take your advice on requesting the test you suggested, it seems like a good idea. This weekend I purchased a home testing kit and sort of did my own tolerance test. I did a sugar load and then took tests every half hour for 3 hrs. I started at 80, I spiked out at 195 1/2 hour after the sugar load. It took about 2 1/2 hrs to return to normal. Does that seem normal to you and could you tell me a little more about the insulin testing you spoke of, is that a special test I would have to request with the GTT. I took a GTT many years ago and they checked sugar levels through out the test but I don't remember insulin testing. My neurologists back then said my test was inconclusive but that it didn't look quite right, I wonder if the insulin testing was what she needed to say for sure. Right after that a issue with some discs in my neck came up and we never got back to my testing. Sorry I'm so long winded Aussie and thanks again for you're help.
That 1/2 hour reading does seem a bit high but the trouble with home meters they can be inaccurate by 10-20% either up or down, they should really only be used as a general guide, nothing more, the glucose tolerance test is much more precise.
The reason I mentioned the insulin levels because they can go up high even before prediabetes can be diagnosed, at first the hormone insulin can produce enough to get rid of excess glucose and sugar levels can look to be normal but as the insulin resistance progresses it gets harder for it to force the sugars into the insulin receptors, that’s when the numbers start to climb, so it would be good to compare the amount of insulin floating around compared to the amount of glucose present, they can draw blood even at fasting levels to check the glucose and the amount of insulin present.
Please let us know how you get on.
Hi Aussie (another australian here) I have been putting up with neuropathy for three years. It has mainly been feet but now it is left hand and fingers as well. It would not surprise me if it is diabetic neuropathy. I had a glucose tolerance test over two years ago.At start my glucose wa 6.3 at 1 hr it was 9.5 at 2hrs 8.2. They did insulin levels in conjunction at start insulin was 42 at 2 hr 220 at 2 hr 290. The report indicated that i had impaired glucose tolerance but not yet diagnostic of diabetes. It went on to say that insulin levels were significantly elevated and could represent the early stages of the development of diabetes.
I don't think my doc read past not diagnostic of diabetes. He has not referred me to a diabetes speacialist or taken any further action.I am taking methotrexate for RA and my rheumatologist just started me on lyrica. It has cut my pain by half and I can now walk a lot further before having to sit.
I am concerned that quite a few medical practitioners ask for pathology but don't seem to have the expertise to interpret it. I don't mean prescribe treatment. I mean realise that there is a problem and refer you to the right specialist. The guy I am with at the moment is sports medicine trained ,when I ask to see a specialist he just says ok ,you find one and I'll write a referal.
I really feel that if you are chronically ill you are considered a hypochondriac. Perhaps I am but if so I'm a bloody good one,I've obviously been able to fake stage 3 colon ca,pancreatitis,gallbladder removal ,two kidney stones,FSGS kidney disease,RA ,insulin resistence and neuropathy. It is sad but true that medicines best diagnostic tool is autopsy. Ron.
Hi Ron, my god mate you would reckon the penny would have dropped when the path report read “that insulin levels were significantly elevated and could represent the early stages of the development of diabetes ", plus the elevated fasting glucose measurement was another big clue.
If it was me I would see another doc and get a repeat glucose tolerance test done, not only for the neuropathy symptoms but all the other possible serious complications that can happen with unattended elevated blood sugars.
Unfortunately there are some real idiots in the medical profession, once I was told by a professor of neurology that he didn't think I had burning feet after giving me a nerve conduction test, this goose didn't even know that a N C test can not test for small fibre damage, you need quanitive sensory testing or better still a skin punch biopsy to test for it, lucky there is some real good doc's still around just got to find one.