I think it could be. But don't take my theory professionally because i'm of course not a professional, am only fourteen years old, and am a male who knows zip about make-up. Anyway back on subject here. Like i said it could be the make-up. Maybe you slept with it on, and some sweat could of caused it to run and irratate your eye or irritate the spot it was on for a long time (or both) which could of caused the bump. As for contacts (I don't have any contacts but i'll take a shot at this) you should take them out during sleep. Closing your eyes for a long time with contacts in (and after having em in all day) will start to make your eyes feel very uncomfortable. Hope i helped. Remember i'm not a professional!
Thanks.
CaseyP