I had an older thread which explains my situation up to this point, but I have been sick for over 2 years and doctors had no clue as to what was going on. I finally went to doctor that found something, he ran a blood tests for mycoplasma which came back positive for an acute infection. I still have to go back for lyme and HIV and some more mycoplasma blood tests. He has put me on doxycyline 100mg 2 times a day for 3 weeks to see what happens. The thing is that I feel severe severe irritation and tingling all over my body, finger tips hardening eyes and gums irritated as well. These are symptoms that I had prior to taking the meds, what I would like to know has anyone gone through something similar to this, as I probably have something else that has causing the mycoplasma infection. The irritation and pain is the worse part of it, it comes and goes but when it comes it is really bad. Any suggestions also on further tests to take?