I am hoping someone can help me. I suffer from tongue swelling for no apparent reason. I am taking Plaquinel daily that is supposed to help. Prednisolone and adreniline do not help once the swelling has started. The doctors can find no reason for this happening. It is very frightening when I can't breathe and would love to know other people are suffering this the same and what they do. It is not seasonal. The only thing different since this started 5 years ago is I has a hysterectomy. Hormonal? I can't get any straight answers.