Hi Bill! Welcome to the boards! I'm not a truck driver, but I have had plenty of joint issues. I had a total hip replacement at 46 yrs. old. I also have osteoarthritis in several other joints as well and I'm no stranger to lower back pain. I'm not sure what the drug is you're talking about--is it over-the-counter? My orthopedic surgeon recommended taking Glucosamine/Condroiton which is found with the vitamins in any drug store. It is safe and there aren't any side effects I know of. My dog even had to take it! It helps with joint pain, for sure. If you are sitting for long periods of time, you may need to do some exercises to STRENGTHEN your lower back muscles. Do an online search for lower back exercises and I think if you do them faithfully, you may have a lot of relief from pain. Of course, if you're not a lot better soon, you should probably see a doctor to rule out anything more serious such as disc problems, etc. (I'm assuming this didn't come on suddenly, like a kidney infection, stones?) Good luck and hope this helps!