Re: pain and prednisone
It's called "rebound phenomenon". Your body becomes dependent on the dosage and when you start to go down, if your body doesn't take up the slack, you suffer from rebound. It's your body reacting to the lack of cortisol in your blood.
You body makes it's own cortisone in the form of cortisol and other chemicals and when you supplement it, the body assumes it doesn't need to make it and stops. When you reduce the amount, the body has to kick start it's own production and sometimes it doesn't or is doesn't make enough to compensate for the amount. The big fear is that the body never starts making it and you are now dependent for life.
Always taper very, very slowly if you have been on for sometime. It's the reason so many docs now do short, fast "bursts" of pred. I know I've had times when I've had to go down literally 1mg/week and even stop for a while at certain points and allow my body to acclimate.