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Old 09-30-2010, 09:01 AM   #1
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safeuse78 HB User
The Great Suboxone Contradiction.

As any Suboxone patient knows, there are two active ingredients in Suboxone: Buprenorphine (a partial opiate-agonist) and Naltroxone (an opiate-antagonist/opiate-blocker).

We all know that when we are on Suboxone, at least a decent sized dose of it, we can't get high on other opiates. You can try as you might. Pop 100 oxycodones or shoot 100 bags of heroin but nothing happens. Your opiate receptors are officially BLOCKED. No entry allowed, therefore no high.

My question is this: If the Naltroxone found in Suboxone blocks all opiate-agonists from entering your system, as I can verify it certainly does block them, how does the Buprenorphine (a partial opiate-agonist) find its way into my brain's opiate receptors while other opiates can't?

I have never understood this, nor have I seen the topic addressed in any forum. If anyone could shed some light on this I would greatly appreciate it.

Be safe, people.

 
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Tags
buprenorphine, naltroxone, opiate, receptor, suboxone



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