I am not sure about actonel, but I can tell you that my experience with BOTH Boniva and Fosamax was joint pain. I felt as though I aged over 20 years in a very short time period (hey, I thought this medication was supposed to HELP you and not age you

) I believe that all three medications (Actonel, Boniva and Fosamax) are under the classification of Biophosphonates and one of the side effects can be joint pain. I decided, due to the long half-life of Fosamax to discontinue this medication since I was experiencing side effects. For right now, I am not on any medication. I am contemplating going on Actonel, although I am not sure since both other medications had side effects for me. Does anyone know how long Actonel remains in your system? I am very interested in hearing how others respond to this question too.