Shoreline

Hey JCF, I was taking the same dose of Kadian as Otter, 200 X 3, It's a 12-24 hour med but the idea was to maintain a smother serum level and prevent the ups and downs, which it did. I never felt a dose whereoff or kick in. My insurance changed and wouldn't cover Kadian so I swithced to the exact same dose of generic MSC, It worked just as well, the only diffewrence is MSC isn't forgiving if your late or miss a dose, You will always have some Kadian in your system taking it 2 or 3 times a day, with MSC , there is a definite beginning and end but dosed 3 times a day really wasn't that noticable and worth the 1400 it saved me. When push comes to shove, they are both morphine, the number of mgs was the same, the relief was the same, you just have to take meds on a more exact schedule. MSC does wear off after 8 hours and then it's hard to get things under control again.

If you have a huge copay difference, that creates a financial burden, your wouldn't be missing out on much with most of the genric MSC products available.

Personally I avoid Mallinkrodt generic products after a bad experience with thier methadose and their generic roxicodone. Mallinkrodt stretches the FDA guidlines to the absolute limit as far as allowable variances with generics to save a few pennies, but those pennies add up.
They are allowed +20% to -20% of active ingredient because you still get the same basic serum ranges when testing a large group of people varrying in size, weight, metabolism and blood volume. Don't believe it when a pharmacist says they are all the same, they get paid topush generics that have a much higher gross profit margin, and I mean GROSS. LOL So paharmacist have a buonus incentive to ush genericsand claim they are exactly the same. I don't consider +20 or -20% exact and whe you switch from one generic t the other you could have a 40% differnce. That plus 20 -20 is a comparison to the proprietary drug "name brand" they don't compare generic to genric so if one is +20% and the other generic is -20% you can experience withdrawal from a 40% variation in generic products that can cause wthdrawal. I have.

Whatever generic you choose if you do, stick with it, don't bop from one to the other because all generics are not the same.

Good luck, Dave