wirry1422

I just wanted to update everyone who has had an experience in the continuing saga of Oxycontin brand from Purdue and Oxycodone ER generic from Endo. I spoke to my doctor at my last appointment and I informed him that last month, the pharmacist had dispensed the oxycodone ER from Endo. I told him that the pain relief is noticeably different (at least a 25% increase in pain) and I have also experienced more nausea since taking the generic oxy. The doctor appologized for my experience and said I am no less then his 11th patient to compain about the ineffectiveness of the generic oxy within the past two months. He told me that he has reviewed the package insert from Endo and compared it to the inactive ingredient list from Purdue and he believes that it is the use of huge amounts of cheap filler in the Endo tablet that is causing many of the differences, as well as the fact that the FDA allowes a large margin for the actual amount of medication per tablet, and endo is probably at the lowest end of the allowable amount. He also said differences in the chemical synthesis of the oxycodone between manufacturing plants can cause differences as well, and perhaps Endo's quality control was not perfected for the generic Oxycontin in their rush to bring a competing product to market against Purdue. Nevertheless, he told me that in the future he would sign all my scripts for oxycontin as "Do not Substitute" and "Oxycontin brand only" so I fortunatly won't have to go thru that experience again. It was really disappointing, especially considering that the price difference in Purdue's and Endo's Oxycontin is negligeable.