The way that I understand it, keep in mind that I'm not in the medical field, is that the meds don't affect the pain, it affects the part of the brain that tells you that you have pain. So really it does just make you not care as much about the pain.
Meds like Tylenol and Ibuprofen are differrent, they acutally affect the areas of the pain, such as inflamation so that makes the pain go down.
It's a very basic explanation and I'm sure someone will come along and give a more detailed response but that's it in a nutshell as far as I understand it anyway.
Certain meds affect certain parts of the brain as well, that's why some meds work better for nerve pain and some work better for acute surgical pain.
I forgot to tell you what meds I'm on, currently I'm on the Duragesic patch 75mcg every 48 hrs and just today my GP gave me a prescription for percoset 5/325 50 tablest to help me while I'm on vacation. I'll be travelling for 12 days 5 in Phoenix to visit my Dad and then 7 in Las Vegas for the Comedy Festival as my husband is a stand up comedian and I want to be able to keep up with them and not be miserably in pain. I feel that I'm undermedicated at this point, that I could and should be able to do more with my life if I had better meds, but will be addressing that at the end of Jan when I see my PM.
JeanneO