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Old 03-18-2007, 12:22 PM   #1
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dani808 HB User
Question Question on tolerance

I have a question to someone with experience with tolerance issues. I am currently on the 30mg Oxycodone (Roxicodone) short acting (2 - 4 times a day), for pain from my back surgery. Everything was fine at first but the dosage keeps getting adjusted as my tolerance increases. When I had my first surgeries I was on Oxicontin and Actiq for breakthrough and it was horrible coming off of that so I asked not to be put on oxicontin. Instead, I chose the oxicodone with actiq. I have stopped taking the actiq and chose to just take the 30mg oxicdones. But that is now not working. I have been steadily increasing and find now that it takes 3 to get substantial pain relief. (120mg 3x a day) I have tapered back a few times but it only takes a few days for your tolerance to get right back where you left off. I only have a bout 2 more months of recovery and want to get through this period without oxicontin and without fentynl. At what level of this oxicodone can I go to before I have to quit taking this? I mean, can I just continue to climb steadily, and is there a point where I can't take it anymore? I am afraid to tell my doc because I know she will switch my to something stronger and I would rather just stay on this and increase the dosage as needed if that is okay. (under the docs supervision of course) I don't want to go through oxicontin WDs again. If there is room for me to still increase on this med, then I will go talk to her about doing it because then I can still say no to stronger meds.
Thanks for the help!

 
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Old 03-18-2007, 05:23 PM   #2
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Tripletmom HB User
Re: Question on tolerance

Hi Dani~

First of all, you are aware that oxycodone and oxycotin are one in the same medication. There are many different names, brands, strengths and such, but the only difference in oxycodone and oxycotin is that one is IR Instant Release and the other is ER Extended or Slow Release...so if you had difficulty getting off of the oxycontin, you may find the same problem with the other, unless of course the strength is significantly less. As far as I know, w/d is w/d in any opiate, although some may find that different kinds are worse or better then others.

As far as tolerance goes...that's a given. And again, for each person, it is different. The problem is, that everytime we take an opiate, it multiplies the receptors in our brain...before ever taking an opiate, our recptors are like virgins and it only takes a small amount to cover those receptors, but with every opiate we take, they multiple and multiple to the point that we need more and more medicaton to fill all the receptors. I know that taking a "holiday" from meds, if possible can be helpful, although I am told that it only takes so long for one to get back to where they ended.

The reason that Dr's don't want to continually increase ones meds, especially for those that will might be on them long term, is that in the end, there will not be enough meds to control the pain b/c the receptors are saturated...I think some ppl think that the Drs are just being mean, and I know that there are some out there that are (been there, met them) but for the most part that is the reason why.

I know that I am in the same boat as you...and I actually am thinking of talking with my Dr tomorrow about tolerance and reshaping my med routine. I have been on the patches and oxy for breakthrough pain for the last 4+ years without a change or increase, but it is not doing what it is suppose to do any longer. Instead of increasing my dose, I might change meds for a couple months and see if that works, and then maybe go back...we'll see what she says.

I probably didn't answer your question, and maybe somebody else can help you better...I think with each of us, it's just such a personal situation and what fits well for one, doesn't always fit the other.

Good Luck,
Dani

 
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Old 03-18-2007, 08:39 PM   #3
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Lightbulb Re: Question on tolerance

Tripletmom,

Actually you helped me very much. I did not know that oxicontin and oxicodone were the same thing. Now I at least I wont be thinking that being on oxicontin is so bad. (something I think the media does to us anyway by making us feel guilty about being on it) Like you, I used to be on the durgesic patches but I hated that sometimes I would feel fine and the mext minute, BAM, I would be all sedated. Plus, I travel a lot and had trouble goign into Italy. The seized my patches and Actiq and within 24 hours I was in a scarey Florence hospital going through WDs with nothing to help. That is why I am trying to be so careful this time. I truly hate the control these meds have over us, and am trying to find as many alternatives as I can.

I think I will go back to alternating between 2 different meds again. It seems that it confuses that body enough and doesn't allow your body to get too used to one or the other too quickly. I will talk to my doc tomorrow and see what she recommends as a secondary medication.

Thanks again!

 
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Old 03-19-2007, 01:48 PM   #4
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Tripletmom HB User
Re: Question on tolerance - Dani

Hi Dani~
Glad I could help...it gets SO confusing with all the different types of medications...some are named by their generic name, some by brand name...I started to go online and look up everything I was getting...so that might be something to do as well.

I am so sorry about your trip to Italy...OMG, I travel a lot as well and can't even imagine that. Infact, we are leaving on a cruise at the end of the week, going through the Bahama's and such, and my Dr has always told me to make sure I keep all my meds in the bottle they came in. I also used to be a flight attendant and I had some friends that would keep their medications, everything from pain meds to vitamins in one bottle and several were taken away by customs....unreal!

I went to my Dr today, and finally got the courage to tell her that my meds weren't helping like in the past. I even admitted that I didn't want to "rock the boat", because I am fearful of loosing what I have. Thankfully, I have not had an adjustment since I came there 3 yrs ago and even before that, so we agreed that it might be time for some RFA injections that have helped in the past, and she also increased my breakthrough meds, giving me 2 extra a day....I am very thankful for that. She didn't want to "up" my Durgesic, and I was fine with that. It wasn't as if the pain was breaking through more, it's just when it did, it was hard to control.

Well, let us know how things go at your appointment...maybe you could look into some procedures like an RFA, if that is possible. It is when the nerve endings are burned to help control the pain signal. It sounds sooo much worse then it really is. I would rather have that done, then my teeth cleaned...LOL

Take Care,
Dani (yes...my name is Dani as well)

Last edited by Tripletmom; 03-19-2007 at 01:50 PM.

 
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Old 03-20-2007, 02:35 AM   #5
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Query HB User
Re: Question on tolerance

Quote:
Originally Posted by dani808 View Post
Tripletmom,

I think I will go back to alternating between 2 different meds again. It seems that it confuses that body enough and doesn't allow your body to get too used to one or the other too quickly. I will talk to my doc tomorrow and see what she recommends as a secondary medication.

Thanks again!
Hi

What meds did you alternate, and how does that work?

Thanks

 
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