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Old 04-16-2008, 06:13 PM   #1
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New Patch in the pipeline of new products

Transdur-sufentanil patches, a transdermal patch for sufentanil, is in clinical trials. In 2005, a company named "Durect" entered into an agreement with Endo Pharmaceuticals granting Endo exclusive rights to develop, market and commercialize TRANSDUR-Sufentanil in the U.S. and Canada.

In 2006, Endo and Durect successfully completed the first clinical trial of the Phase II program for TRANSDUR-Sufentanil using patches manufactured by us to evaluate the transition of chronic pain patients from Duragesic to TRANSDUR-Sufentanil.

Evaluation of plasma level data indicate that TRANSDUR-Sufentanil performed as designed by achieving its target delivery profile of providing a rapid onset of drug and a delivery of very consistent blood plasma levels. The product was tolerated well with no apparent safety issues over the four-week treatment period.

For us as patients, what's really encouraging is that the patch is approximately 1/5th the size of Duragesic, and lasts for 7 days. Endo is conducting Phase II studies designed to evaluate the conversion of chronic pain patients treated with other oral opioid products to TRANSDUR-Sufentanil.

Sounds encouraging.....Another potential weapon in the fight against chronic pain!

Ex

 
Old 04-16-2008, 06:40 PM   #2
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Re: New Patch in the pipeline of new products

Sweet. Now I wonder if they can actually get the patch to stay on for 7 days without irritation or falling off. that will definitely be the test. I had to do a quick search on what this was and found out

Sufentanil is a synthetic opioid analgesic drug approximately 5 to 10 times more potent than fentanyl. This is probably the reason that it is 1/5th the size. Good to know about though

brian

 
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Old 04-16-2008, 06:58 PM   #3
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Re: New Patch in the pipeline of new products

Did you see a picture of it? Very small...About the size of a fingernail.

Ex

 
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