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Old 05-02-2008, 07:29 PM   #1
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Oxycodone or Morphine

Does anybody know which is actually the `stronger` of the two: oxycodone and morphine?


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Old 05-02-2008, 08:28 PM   #2
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Re: Oxycodone or Morphine

I was told by my doctor that morphine is a step up from oxycodone which is apparently why I was put on the oxycodone instead. I could be wrong though, see what everyone else says

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Old 05-02-2008, 08:43 PM   #3
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Re: Oxycodone or Morphine

I believe it's gonna depend on the strength.

Old 05-02-2008, 10:11 PM   #4
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Re: Oxycodone or Morphine

I think individual tolerance can play a role in it too. Sometimes what is strong to one is not strong to another.

Old 05-02-2008, 10:46 PM   #5
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Re: Oxycodone or Morphine

Milligram to milligram oxycodone is 1.5 times stronger than morphine.
At least that's what I've been told...please correct me if I have it wrong.
undiagnosed lung and back pain after pneumonia in '03, tmj, migraines,(two failed surgeries for) Kienbock's disease

Old 05-02-2008, 11:10 PM   #6
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Re: Oxycodone or Morphine

I've heard the same thing as Mush. (trowftd3) I believe both Ex and Dave have told us that in one thread or another.

Old 05-03-2008, 08:23 AM   #7
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Re: Oxycodone or Morphine

Yes, Oxycodone is approximately 1.5 X stronger than Morphine. Doesn't matter on the dose....It's proportional.

Many think it's the other way around because the term "morphine" sounds impressive. Also, morphine was the "original" pain med years ago, so all the conversion tables & etc. use morphine as the baseline. Oxy is a synthetic med developed specifically (as were other like hydrocodone) to address tolerance, side effects, & etc. This all goes back to the discussion on opioids vs opiates.


Old 05-03-2008, 04:56 PM   #8
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Re: Oxycodone or Morphine

Morphine is one of the natural products that come from the opium poppy. It's called an alkaloid, along with codeine and thebaine.

You are probably familiar with codeine. It's much weaker than morphine.

Thebaine is the other major alkaloid found in opium. From thebaine they make oxycodone. So oxycodone is semi-synthetic, as it is derived from a natural substance.

Morphine is called the "gold standard." As Ex wrote, when they compare narcotics morphine is the one all others are compared to. In such a comparison, 15mg of morphine equals 10mg of oxycodone.


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