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Old 05-19-2008, 03:54 AM   #1
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Is it just me, or does oxycontin not even last 8 hours?

Most recently, I was on 15 mg twice a day, and I felt like the oxycontin worked for a few hours and then left me without pain coverage for the rest of the 12 hour period. My PM suggested that we try three doses (so 10 mg three times a day -- same total daily amount) and then titrate up. At this stage in my PM experience, I'm trying to minimize my medications even if I'm left with a good amount of pain (I realize that this is not always the smartest pain control approach, but I know it's easier to start low and go up high then the other way around -- just my personal view for myself at this point). Anyway, I was surprised to see that the 10 mg tablet did take just enough edge off the pain. Unfortunately, it only lasts for about 4 hours. I understand that LA medicines often work only 8 instead of 12 hours, but it puzzles me how sometimes the tablets seem to work only 4-6 hours.

At my next appt, my doctor is going to suggest we up my dose to 15 or even 20 times 3 times a day in order to get good coverage all day long, but I'm wondering if as a preliminary step, I could try 10 mg * 4 times a day. Has anyone had dosing this frequent on Oxycontin? 10 mg * 4 times a day is 40 mg total, still less than the 45 mg from taking 15 mg three times a day. So is my PM likely to find my 4 times a day dosing schedule to be totally outside the PM norm?

 
Old 05-19-2008, 06:24 AM   #2
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Re: Is it just me, or does oxycontin not even last 8 hours?

I take mine 4 times a day. In the past it was helpful but right now it is hard for me to tell because I am in a big flare for the last 3 weeks.

 
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Old 05-19-2008, 06:35 AM   #3
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Re: Is it just me, or does oxycontin not even last 8 hours?

I was on OC for several years and it didn't work very well. Started @ 2x, went to 3x...Never tried 4x because 3x didn't work well.

My PM Doc, an anesthesiologist, said he doesn't think it's anywhere near a 12hr drug. He thinks 8 @ the most. Since going on the patch, I have had remarkable improvement and don't even know it's on. The patch gives you very precise dosing each hour 24/7. Many who are on the patch don't need BT meds. Everyone is different though.

You might try 4x. I've also heard that Opana works much better than OC, but I haven't tried it.

Good luck.

Ex

 
Old 05-19-2008, 07:09 AM   #4
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Re: Is it just me, or does oxycontin not even last 8 hours?

Mark, First, It depends on the person and how their body metabolizes opiates/opioids. In most cases with LA meds, a short acting or breakthrough med is used for breakthrough pain. You haven't mentioned whether you take a BT med.

Second, Almost everyone I know who takes Oxy, concurs that it does not last the full 12 hours that the pharmaceutical companies claim that they do. This being said, with the addition of the BT meds, they should stretch out to 7 - 8 hours of coverage.

I have heard of Oxycontin and other like meds being dosed 4x/day for some. It usually depends on 1) How the doctor feels about doing so and 2) if the insurance company (if applicable) will allow or approve it. My PM doc had to obtain authorization to increase my Oxycontin to 3x/day and has to renew this authorization every 6 months.

I would discuss this at length with you doctor and see what he wants to do. I hope this helps a little. Take care. CMP

 
Old 05-19-2008, 10:01 AM   #5
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Re: Is it just me, or does oxycontin not even last 8 hours?

I was started on 30mg twice a day. That didn't work at all so my doctor raised it to 30mg three times a day. After a week of that I realized it wasn't working as well as the doctor wanted it to work (he didn't want me to have to take BT meds unless I did something bad to cause it). So he had me try 40mg three times a day and said if that didn't work to try 30mg four times a day.

A little back ground (before taking the oxycontin I was on 50mcg fentanyl patch which worked well to kill the pain but caused lots of other issues so I had to stop using it). My doctor later told me that because I was on 50mcg of the patch that we had room to up the dose of oxycontin to around 110-120mg but wanted to start me out at the lower dose and then raise it as needed. The 40mg three times a day still didn't work. Just like you I don't seem to get the second release of the oxycontin so we settled for 30mg four times a day. But to be honest this still doesn't work as well as the patch. At best my pain is down to 2-3, I know I shouldn't expect to have 100% pain reduction but with the patch that is exactly what I had.

The worse part right now for me is my doctor has told me he is at the max level of pain med management he is comfortable doing, if I need more, then I'm going to have to start seeing a PM doctor that does nothing but manage pain meds. I really don't want to do that. With the issues I had with the last specialist, him giving up on me and handing my PM med management back to my GP because I wouldn't let them operate on my back (50/50 chance it would work, 20% it would make things worse and only a maximum of nine months relief from the operation was not good enough for me to let them operate).

Anyway, sorry for rambling. Maybe oxycontin isn't the right med for you, I'm thinking it isn't the right one for me but I'm too afraid to change now. I would suggest talking with your doctor if you can. Let them know that for some reason it seems like the time release mechanism that is used for the oxycontin doesn't seem to work for you.

 
Old 05-19-2008, 10:07 AM   #6
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Re: Is it just me, or does oxycontin not even last 8 hours?

Mark,
I started 20 mg Oxycontine (LA)every 12 hours and than BT Oxy (15-22 mg). If I would be just on LA, did not help my pain at all. I had to take 2-3 times BT.
I called him and he upted to 20mg every 8 hours. I do still need BT but only I would say 1-2 times a day. In a bad days still need more thogh.
I have to fight myself not to take more than that BT, because pain is pretty bad still, but I hate to take more than this.
I always wonder how come it doesn't work for me as well as Percocet or Fentanyl patch LA. I had it for a short time but saw a big difference between 25 mg of Fentanyl patch as LA and 20 mg of Oxy as LA.

I have an app tomorrow with my PM and will bring his attention to this matter; hopefully he will have better solution for my pain.

 
Old 05-19-2008, 11:30 AM   #7
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Re: Is it just me, or does oxycontin not even last 8 hours?

your dose is fairly Low Mark. I take (3) 40 mgs tabs of oxycontin 3 times a day and than I can take up to (4) 5 mgs of B/T meds of oxycodone if I get afternoon pain increase. the med for me last a full 6-8 hours but everyone is different. i am taking on some days a total of 140 mgs a day so if you have CP your dose is low but as you know a PM Doc will start out low and SLOWLY work your dose up. this can take months and months to get the right regiman for you and your pain. It takes a lot of patience and you are just at the very beginning so please hang in there and communicate to your DR that your not getting good pain coverage and that the med is not lasting long at all. It took me 3 to 4 months to get my dose right so patience is a virtue here. it sounds like you have a good Dr who is willing to work with you so that is great news for you. Hang in there.

SS

 
Old 05-19-2008, 01:06 PM   #8
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Re: Is it just me, or does oxycontin not even last 8 hours?

One thing that hasn't been mentioned yet, are you taking name brand or generic? I've been on both and can tell you without a doubt the name brand works much better.
Fred

 
Old 05-19-2008, 03:24 PM   #9
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Re: Is it just me, or does oxycontin not even last 8 hours?

Thanks for the info. my doc also gives me 70 breakthrough pills per month (5 mg oxycodone) to use as needed) (up from 60 the previous month). I use the brand-name (I didn't know generic oxycontin existed anymore). However, in the oxycodone I use generic b/c the pharmacy says brand doesn't exist (i.e., the claim roxicodone or oxyIR is just another generic). In oxycodone, I've used the Amide and Mallincroft. I feel like the Amide is far more effective but it could be my imagination. It seems like all the major pharmacies stock the Mallincroft version.

 
Old 05-19-2008, 08:31 PM   #10
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Re: Is it just me, or does oxycontin not even last 8 hours?

That's correct Mark, generic oxycontin is not being produced at this time, because of Purdue's lawsuit. Unless a particular pharmacy still has some of the generics left in their inventory, everyone would be receiving the brand only.

 
Old 05-26-2008, 05:02 AM   #11
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Re: Is it just me, or does oxycontin not even last 8 hours?

My PM doc told me over a year ago that Oxycontin-generic was no longer available.

I use a major nationwide pharmacy. Why am I still able to get the generic?

(putting on my Sherlock Holmes hat now)...

Either the statement was incorrect OR
These pharmacies are stockpiling meds.

I'm taking 60mg Oxycontin-generic 3 x daily. PM just added Baclofen 2x daily. I'm finally, after over 4 years, getting some relief.

My Oxycontin-generic only lasts about 6 hours.

If they are giving us "old" meds, how are we going to respond to a "fresh" batch? With medication like Oxycontin, I'm thinking we might be in for a bit of a shock.

Am I being a bit melodramatic here or should we be concerned?

Eva

Last edited by Eva32159; 05-26-2008 at 05:52 AM. Reason: better wording

 
Old 05-26-2008, 08:42 AM   #12
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Re: Is it just me, or does oxycontin not even last 8 hours?

For some reason it doesn't work on me as well. I thought it will be a better drug than Percocet, but instead I have to admitt Percocet worked better on me than LA and BT Oxy.
Since I am on it I did not have even one day, one hour a day when I could say it helped me with pain. At least it would take me to a bearble levels for couple hours a day - I would be happy, but it does not happens.
I don't understand one thing and maybe someone can explain to me; if so many people have same experience with this med. as I have, why my PM DR's face was suprised when I told him that I don't feel much relieve from it. He gave me 20mg of LA Oxy every 8 hours and Bt 15-22mg (depends on pain) up to 8 times a day. Why do I need LA than if I can take BT so often? Does it mean that he knows LA is not working well on his patients?
I am very suprised since it suppose to be more effective than Percocet, but for me absolutely NOT.

I am glad I can read your opinions on this matter, clears some questions for me.
Thank you!

 
Old 05-26-2008, 10:47 AM   #13
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Re: Is it just me, or does oxycontin not even last 8 hours?

Eva, The lawsuit stated that pharmacies could use up their current stock of generics, so your pharmacy must have had quite a bit. I can't say this means it is "old" or "expired", but I doubt that any pharmacy would take that risk. (At least I would hope they wouldn't) The brand name, in my opinion, works much better than the generics I have taken, but not so much more that a lateral change would make you feel "over-medicated".

Moldova, I think some docs just get "stuck" on one or two meds that they like to prescribe and because of your many allergies/bad reactions to some meds, he may be a little skittish about changing anything right now. Not your fault, I know, but that is the only thing I can think of, in answer to your question. I wish more docs understood that what works for one patient, may not for another. Oxycontin works quite well for me, but I know others have had less luck with it.

I sincerely hope that your doc can begin to listen to your concerns and take a more proactive approach to your pain. It is not right for you to have to be at the pain levels you are right now. I always include you and others in my prayers, specifically when I am asking for appropriate pain relief for all of my friends here.

Take care and God Bless, CMP/MM

 
Old 05-27-2008, 12:24 AM   #14
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Re: Is it just me, or does oxycontin not even last 8 hours?

I also take the generic of Oxycotin. My Dr. increased to 20mg every 12 hours. I don't notice it helping the pain at all. No relief. The Oxycodone 4hr break through meds seem to work better. Maybe because I took the Oxycodone for so long before going on the Oxycotin generic I have built up a tolerence. I don't know what the Dr. will do next. I thought the Oxycotin would be a miracle drug but it's not.

 
Old 05-27-2008, 06:36 AM   #15
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Re: Is it just me, or does oxycontin not even last 8 hours?

Quote:
Originally Posted by Eva32159 View Post
My PM doc told me over a year ago that Oxycontin-generic was no longer available.

I use a major nationwide pharmacy. Why am I still able to get the generic?

(putting on my Sherlock Holmes hat now)...

Either the statement was incorrect OR
These pharmacies are stockpiling meds.
The ruling said that the manufacturer could continue selling the product they had in the pipeline until it was all gone....They couldn't make any more. So, yes, some wholesalers and chain pharmacies had quite a bit of inventory.

Quote:
Originally Posted by cmpgirl View Post
The brand name, in my opinion, works much better than the generics I have taken, but not so much more that a lateral change would make you feel "over-medicated".
Remember, the "brand" could be as much as 20% stronger.

Quote:
Originally Posted by cmpgirl View Post
Moldova, I think some docs just get "stuck" on one or two meds that they like to prescribe and because of your many allergies/bad reactions to some meds, he may be a little skittish about changing anything right now. Not your fault, I know, but that is the only thing I can think of, in answer to your question. I wish more docs understood that what works for one patient, may not for another. Oxycontin works quite well for me, but I know others have had less luck with it.
Very good point(s).

Quote:
Originally Posted by Moldova View Post
Why do I need LA than if I can take BT so often? Does it mean that he knows LA is not working well on his patients?
If you're taking some form of Oxycodone up to 8 times a day, then you really don't need a LA med. A LA med is so you don't have to take meds so often. A stronger does of OC may work. But, I'm not sure exactly what you've tried & etc.

Ex

 
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