They are two totally different pain meds. Oxycodone which is a base medicine used to make oxycontin, percocet, roxicodone is a codine based medicine meprozine is in the demerol family but never did anything for me in fact demerol does nothing for me even when I have recieved it intravenasly. Ex what do ya know about meprozine??
Meprozine is meperidine (Demerol) and promethazine. Demerol is usually given with promethazine. The promethazine tends to augment the pain relieving effects of Demerol and add to the sedation, which in hospital post-op settings is usually welcome.
Oxycodone is derived from thebaine, an alkaloid of opium. Oxycodone is about 50% stronger than morphine. Demerol is about one-half to one-third as potent as morphine, so oxycodone is clearly the stronger of the two meds (meprozine vs oxycodone).
However, everyone reacts to these meds differently. I greatly prefer demerol to morphine when recovering from surgery, others prefer something else.
Pethedeine is generaly frowned on for long term pain control, because of its short (2-3 hour) duration of action, toxic metabolite (norpethedeine) and high propensity to produce drug dependence/addictive beheivior
Which one is stronger depends on the dose
For short term (24 hours) pain releif, pethedeine/meperidine is fine, for more than that, oxycodone, morphine, hydromorphone etc are generaly prefered.
I've just found that people are so different when it comes to reacting to meds.
Look at me - for me, IM demerol works better than IM morphine, even though the demerol is weaker. Yet, when it comes to CP meds, I use oral morphine and it is better for me that way. I've tried oral demerol but it's much, much weaker when taken orally. It takes about 300mg to get the same pain killing effect of a 75-100mg IM dose. And, as aussie pointed out, its metabolites are toxic if taken any longer than a few days.