| Re: oxycodone=oxycontin
The exact release mechanism is a trade secret...You cannot find the information anywhere. I've heard some say that half is released upon taking the med and the other half is released approximately six hours later. So, for a 20mg, 10mg would be released immediately, and then the other 10mg six hours later. However, my PM Doc told me that 10% is released immediately and then the 90% released proportionally over next 10 hours.
Regardless of the forumla, it is designed to release the Oxycodone over time via the time release mechanism in the pill. This is what makes the med long acting. If you read the prescribing white paper from the manufacturer, it will tell you that for any given dose of OC, the blood plasma level (BPL) is higher on OC than the same amt taken of Oxycodone instant release over the same period.
For example, OC 10mg taken every 12 hours results in a higher BPL than if you take 5mg of Oxycodone every 6 hours. Not only does the BPL get higher, but is sustained. This is why the med is so effective for many.
Brian is correct in that most patients report that the med does not last 12 hours. 3 x per day, or every 8 hours, has become pretty standard by many.
Hope this answers your questions.
Regards,
Ex
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