Originally Posted by lifeaftr40
What IS the difference between the two ?
Opana is a relatively new LA med for chronic pain. Its "claim to fame" is that it supposedly targets a different receptor in the brain....One that doesn't cause euphoria, and therefore is less addictive in nature. It's also very expensive.
The problem with this concept is that although that may be true, the receptors that they don't target, are the primary pain receptors....And the ones most likely to be sending out pain signals. Therefore, many people who take the med report that it doesn't work well....Or even work at all.
I've never tried it, but I have done research on it and if you do a search on this board, you will see that the feedback is overwhelmingly negative. Just type "Opana" in the search box and go from there.
Ms Contin is LA morphine. It's been around quite a while and is available in generic and is very affordable. Other LA oral morphine products are "Kadian" and "Avinza." All three are basically the same. All three have the same active ingredient, or oral morphine. Ms Contin comes in a pill form, while the other two are capsules with very tiny beads in them.
Ms Contin is every 12 hours. Kadian is every 12-24 hours and Avinza is every 24 hours. Most patients report, however, that all three don't last as long as they claim. But, that should be no surprise to anyone who has taken LA meds such as Oxycontin....It doesn't last 12 hours as Purdue Pharma claims.
LA Morphine works very well. The only negative is that it has poor bioavailability which means it isn't absorbed well via the stomach and GI tract....Therefore, you need more of the med, to do the same work as a good bioavailability drug. Oxycodone, for example, has excellent bioavailability, so you need less. Your Doc should know the transition table.
Hope this helps.