Adding Dex "yes The active ingredient in cough syrup" to meth isn't really going to give it a property it doesn't already have. That is blocking the NMDA receptor. It may increase meths blocking ability so it somewhat depends of your dose of methadone.
My dose is rather high so adding 90 mgs of dex didn't really do anything the meth wasn't already doing. However if your dose is relatively low, say 30-40 mgs a day then a boost of pure dex 30mgs TID may help with tolerance and pain perception. Dexalone is a 30mg capsule of pure Dex. TID is the standard dosing instructions. It's not cheap though so you would have to have a noticeable improvement to make it worthwhile.
Ketamine is also a strong NMDA receptor blocker but I don't think your doc is going to want you to take street special K to boost the effectiveness of your opiates. Ketamine is an animal tranquilizer that happens to block the NMDA receptor too. It's also a popular designer street drug like ecstasy and GBA.
Perhaps in the future small amounts of Ketamine will be added to LA meds to give them the same NMDA blocking ability.
They are making progress in understanding all the receptors involved in pain management and perception. Unfortunately it's against the TOS to post or cut and paste such articles.
Ketamine is occasionally used on humans to induce a coma to break the cycle of chronic daily migraines but requires use of a vent when you induce a coma.
The best results have been found when adding dex to morphine. Many of the new LA morphine products in clinical trials are being developed with dex.
Using cough syrup that's not pure dex is going to add other meds into the mix that may not be safe, thus the need for a pure dex capsule "Dexalone"
Nyquil is going to add more than just dex, the alcohol alone is going to have an impact on every med you presently take plus the antihistamine will have some impact on your meds.
Talk to your doctor about adding Dexalone to your present meds, other interactions have to be considered before just adding an OTC cough syrup to the mix.
I would post a link about Dex and the NMDA receptor but after my week of reflection
LOL I find it unfortunate that people aren't able to actually help more than just offering a shoulder to lean on.
Talk with your doc about DEX, If your doc actually has an interest in the science of PM he will be up to date on what DEX can do for you and possibly suggest reading material without being punished.
MY ability to post outweighs my desire to back what I'm suggesting with actual aricles or links.
I really am sorry I can't be more help, Shore
Do a search for Dex and opiate interactions.
Or do some research on the NMDA receptor or Ketamine and the NMDA receptor.
[This message has been edited by Shoreline (edited 10-26-2003).]