Opana ER can be fussy. Many complaints when it isn't working, and true believers when it is.....
1) Opana
seems less effective after Oxy or Morphine due to Oxymorphone working on a more select group of receptors.
2) Take with food, Fish Oil, and/or Hydroxyzine.
3) If you are prescribed TID or QID consider IR Generic version which will give more immediate results.
4) Hang in there..... Increase dose if no relief in 2 weeks.