It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Pain Management Message Board
Post New Thread   Closed Thread
LinkBack Thread Tools
Old 04-08-2011, 10:13 AM   #1
Newbie
(female)
 
Join Date: Apr 2011
Location: blaine, washington USA
Posts: 1
orsdln HB User
does fentanyl patch bypass the liver and go directly into the blood stream?

for medicare purpose we are trying to get appeal to continue on fentanly patch (have been taking for 11 years) they want me to change to MS ER when I am already taking 250 oxycodone a monthe so need to know if patch bypasses the liver and goes directly into the blood stream?

 
Old 04-09-2011, 01:33 AM   #2
Senior Veteran
(female)
 
Join Date: Jun 2004
Location: Northern California
Posts: 797
Fiona_Jo HB UserFiona_Jo HB UserFiona_Jo HB UserFiona_Jo HB UserFiona_Jo HB UserFiona_Jo HB User
Re: does fentanyl patch bypass the liver and go directly into the blood stream?


Everything I have read in regards to the Fentanyl Patch is that it goes directly into the bloodstream and bypasses the stomach and liver completely. That is one the the benefits of this type of system. I know for me it has been wonderful. I have been able to remain on the relatively low dose my PM Doctor started me on and I manage to wake up in the morning as close to pain free as I have experienced in many years. Of course there have been adjustments my Doctor has made made, I now change the patch every 48 hours, instead of every 72 hours and I do have a narcotic available in pill form to take for break through pain.

I hope this helps.


~ Fiona Jo
__________________
080807-Cervical-Stim~071707-ACDF-C5-C7 w/instrumentation/bone graft~'07/06 Lumber instrum. removed 05/04-Fusion(DDD/Collapsed Disc L5-S1)08/99-Microdisectomy(Herniated Disc) ~Lupus/EDS,Migraine

 
Sponsors Lightbulb
   
Old 04-10-2011, 04:14 PM   #3
Newbie
(male)
 
Join Date: Apr 2011
Location: SF Bay area, CA
Posts: 2
cleanser HB User
Re: does fentanyl patch bypass the liver and go directly into the blood stream?

It doesn't bypass the liver completely. The drug is still metabolized by the liver it just avoids first-pass metabolism.
The transdermal delivery system allows for higher bio availability (more active drug in your blood stream). The reason why you dont see fentanyl pills is because a large portion of it would be metabolized by the liver into inactive drug.
The lollipops (transmucosal) also avoids the first pass effect.

 
Closed Thread

Similar Threads
Thread Thread Starter Board Replies Last Post
Need help please on fentanyl patch and oxycontin laceymist Pain Management 6 06-24-2011 08:56 AM
Deaths Seen With Fentanyl Narcotic Pain Patch dietcoke Pain Management 6 06-24-2011 06:12 AM
care of fentanyl patch EILEEN 26 Pain Management 4 02-07-2010 03:17 PM
what dose of fentanyl lozenges should i use if i'm on 100mcg of fentanyl patch cazzeem Pain Management 11 12-15-2009 02:08 PM
pain medicine that does not have acetaminophen scooters Pain Management 4 07-14-2009 12:38 PM




Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off




Sign Up Today!

Ask our community of thousands of members your health questions, and learn from others experiences. Join the conversation!

I want my free account

All times are GMT -7. The time now is 02:25 PM.



Site owned and operated by HealthBoards.com™
Terms of Use © 1998-2014 HealthBoards.com™ All rights reserved.
Do not copy or redistribute in any form!