Re: MC1R gene
Has it been confirmed without doubt, now?
Last I heard: It is unclear whether this gene affects basal pain sensitivity or the efficacy of analgesics acting at the more clinically relevant mu-opioid receptor.
There isn't exactly a wealth of information on it out there. If true, though, maybe we can start admitting that not everyone on earth is the exact same bag of bones and things like genes and race really do matter.