Re: Exalgo question
Hi Dean H, Fentanyl is a unique opiatee as far as what receptors it binds too. It's one of the few that has Kappa activity where Dilauaidid has virtually none which means you can expereince withdrawal even given the most generous dose of Dilaudid. You really have to get passed the differential withdrawal before fine tuing and adjusting the Exalgo. You can always adjust but increasing in the hopes of decreasing Fent withdrawal will just make your tolerance higher than if you had toughed out the withdrawal a little lomger.
Good luck, Dave