I have been on 20mg of prozac for one month now. The day I took my second dose, I guess I didn;'t drink enough water, and then I went to sleep. I think the dang thing dissolved in my esophagus, cuz I had the absolute WORST heartburn ever (worse than when I was pregnant). Since then, i haven't been experiencing what I would call heart burn, but I have an on-again, off-again feeling that there is a lump in my throat. The doc said that this could be another manifestation of anxiety, or it could be reflux in the absence of the other "louder" symptoms (burning discomfort, etc). She upped my dose yesterday to 30 mg, since I have been having some really bad panic attacks (I was actually having one at the docs office, so she was able to see me in all my panic-glory,
)I tried over the counter Zantac to see if that helped with this lump-feeling, and it didn't so I don't think it's heartburn or reflux. I know that prozac can occaisionally cause discomfort when swallowing, as well as other GI complaints. It might be worthwhile to take this up with your doctor.