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Parkinson's Disease Message Board
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Old 09-08-2008, 10:32 PM   #1
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Stages of PD??

My husband ws diagnosed with PD at the young age of 48. He is currently taking Sinemet and Azilect for his treatment. His neurologist never mentioned "stages" of PD to us or never referred to us what stage he is in.

What are the stages of PD, and how significant are they to a PD patient?

Thanks in advance.

 
Old 09-10-2008, 07:06 PM   #2
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Re: Stages of PD??

Hi,
My Dr. never mentions staging. In general stagine is not used much any more.
There are 5 stages. 1.)signs & symptoms on one side, mild symptoms. 2.) symptoms are bilateral (both sides) some disability. 3.) significant slowing of body movement,
difficulty walking. 4.) severe symptoms, no longer able to live alone. 5.) cachetic stage, can not stand or walk.
Some people with PD never progress to the later stages and progression varies in rate and from person to person. Not a good idea TO follow staging (unreliable).

Take care
John g

 
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Old 09-20-2008, 02:03 PM   #3
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Re: Stages of PD??

How old is he now? I'm 50 and have had symptoms for at least 4 years but was diagnosed in Jan 07. NOT THE WAY I WANTED TO TURN 50 and enjoy my empty nest!!! If he is newly diagnosed, you might want to get another opinion on meds. A traditional neuro might start with sinemet but from what I've read and info from the docs I've seen you might want to see if some of the newer drugs would be a better starting point. From what I've been told (and group please correct me if I'm wrong), Miraplex/Requip help the body make more dopamine, Azilect helps the body use it more effectively and Sinemet is replacement dopamine. While virtually all neuros have PD patients you might want to find one that is a "movement disorder" specialist.

 
Old 09-20-2008, 10:47 PM   #4
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Re: Stages of PD??

gents. Cogentin, Artane.

John g

 
Old 09-20-2008, 11:35 PM   #5
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Re: Stages of PD??

Hi,
There are 4 classes of drugs used to treat PD symptoms. They work on a
different part of the neurotransmission system. They are; 1.) Replacement
therapy. Sinemet a dopamine precursor (it is cnverted into dopamine).
2.) Dopamine agonists. (Mirapex, Requip) They directly stimulate the dopamine receptors. 3.) Inhibitirs of dopamine metabolism. Comptan
(Entacapone) inhibits the enymye COMP, and Azilect inhibits the enzyme
COMT. 4.) Anticholinergic agents. ( Cogentin, Artane).

John g

 
Old 10-13-2008, 06:06 PM   #6
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Re: Stages of PD??

My brother-in-law is in end stage. He can no longer walk, talk, swallow. It is a rather difficult time. Fortunately Parkinson's is usually a slow progressive disease. In his case at age 77 it only took 6 months. At 99 pounds he is evaporating before our eyes. He is not on medication because unlike most people he has never had the tremors. Does have fixed gaze. When he could walk, he didn't swing his arms etc.

 
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