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Parkinson's Disease Message Board
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Old 11-08-2008, 08:01 PM   #1
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sponge70 HB User
comton

has anyone taken comton. the doctor just gave it to me two days ago, i'm taking it along with sinemet and yesterday and today i got so dizzy i barely made it to the chair.
sponge

 
Old 11-15-2008, 10:46 PM   #2
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Location: palmdale, california, Los Angeles Co.
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oldcow HB User
Re: comton

Hi Sponge'
I have not been posting for some time.
Yes, I have taken Comtan (entacapone). I took it for 2 years and now I take Stalevo 150, whic contains 200 mg of Comtan per tablet.
Comtan has no anti-parkinson action alone. It inhibirts 1 of the 2 enzymes which metabolizes dopamine and levodopa (contained in Sinamet) thus extending the amount of levodopa that is available to cross the blood-brain barrier; this extends the time
dopamine remains active in the brain (substantia nigra and striatum). There is an increased in dopamine elsewhere in the body, whitch causes side effects.
Side effects are more severe at first (usually). To reduce the Sinemet dose reduces
these side effects.
I think Comtan is GOOD drug to extend the duration of Sinemet.

John g

 
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Old 11-16-2008, 01:46 PM   #3
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Re: comton

i called the doctor and told him the compton was making me dizzy, he said just take one in the morning with the sinemet. i don't think the comton made me dizzy because i got dizzy the other day when i was'nt taking the comton. do you get dizzy at times.
sponge

 
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