I just came back from Dynamic MRI , they gave me CD not report yet. Can you or anyone tell me where to look for this adenoma if i have one in CD. If you like i can do webex with you so you can my CD and then point out where to look for tumor. It looks good to me though :-)
Here is what in report , it seems like no tumor but still want to run by the same wording as what in report to you.
"PROMINENT HIGH SIGNAL WITHIN THE POSTERIOR ASPECT OF THE PITUITARY GLAND.WHICH LIKELY REPRESENTS THE POSTERIOR LOBE OF THE PITUITARY GLAND.NO DEFINITE LEISON IS IDENTIFIED. HOWEVER IT IS CONCEIVABLE THAT THIS POSSIBLY COULD REPRESENTS A SMAL PITUITARY LEISON.SUCH ASA HEMORRHAGIC MICROADENOMA OR HEMORRHAGIC/PROTEINACEOUS RATHKE CLEFT CYST.
RECOMMEND FURTHER EVALUATION WITH SPECIALIZED 3-D T2 CUBE IMAGING."
I can tell you what a tumor would look like. It would look like a BRIGHT white shining spot. If your scan is free of these then the initial anomaly was due to some other feature. The Radiologist is speculating that bleeding in the pituitary at the time of the other scan caused the anomaly seen as a tumor. SO this was a good scan. ALWAYS get a second opinion.
MG
__________________
If we learn by our mistakes, I am working on one hell of an education.
Okay so now if there is no tumor , what is next . Why did my proactin slightly elevated , why my testosterone is low then ?. . Even i don't have tumor , can i still have pituitary disorder ?.
Is there any way to restart my pituitary gland function ?. Any restart protocol approach ?. One side i am happy that there is no tumor but other side now i am puzzled then what could be reason for my low testosterone ?.
PLease advise.
Whoa! Okay you have reached the limit of my comfortable knowledge of analysis and care.. I will hazard some rough recommendations. I say you have to trust the neuro on this though.
I can also say that YES you may have mild hyper-pituitarism. They should check your hypothalamus output to your pituitary gland to make sure you do not have some weird communication error going on. Bleeding in the pituitary gland due to impact damage or anemia and other issues can take a while to recover as well.
How do you reset a pituitry gland. Not sure. I would assume you suppress it then let it recover. They did this already though.
You need complete adrenal hormone testing. Have you had an ACTH stimulation test? You may have an issue in your adrenal glands ability to synthesize testosterone. This could be poor communication between hypothalamus-pituitary-adrenals or damage to the actual adrenals.
You have Hashimoto's one autoimmune thyroid issue correct? Then others are probable. The antibodies we can make to kill off our adrenals are ACA adrenal cortex antibodies. You might want to ask for that test as well. I wish I had an answer for you, but I can only give you more questions.
MG
__________________
If we learn by our mistakes, I am working on one hell of an education.
I just got result of my IGF-Binding protein 1 =2.1 (Fasting=10-150,Randon 0-40). This seems to be pretty low , what do you think ?. Do i need any GH therapy which can improve my level w/o comprimising my fertility and also increase my muscles strength.
My estrogen is is also 39 ((0-53), should it be below 25 to maintain my Estrogen and Testosterone level, my last test show total testosterone is 216 (241-837).. Should i start 50mg of zince twice a day to drop down my estrogen level which eventually maintain ratio.
I just schedule Endronologist on Thurday to discuss my course of action to quicklt increase my testosterone and IGF-1 level.
Please suggest any plan you may think can help discuss with doctor
I think you have some estrogen dominance going on that you need to talk to that Endo about. Also getting the IGF up is a must as well. I am not sure if GH will do what you need I would have to look into the mechanism of the GH cycle. I have not looked into that before. I do think you should get a glucose tolerance test with IGF and insulin reaction profile as well. The low IGF and resultant low insulin can explain many muscle issues.
MG
__________________
If we learn by our mistakes, I am working on one hell of an education.
How would i bring my IGF level UP , do we have natural way to do it . I am loosing hope day by day , do you think pituitary is responsible for all these things happening to me or there could be something else going on.
I was reading Testosterone syndrome by Eugene Shippen , she mention in one of her chapter to use Zinic 50mg twice /day, to maintain Estrogen and testosterone ratio, she also mention above 30 in men consider high.
The GH is pretty sensitive one , so i am curious if other hormones regulate by pituitary started to work , will my GH will increase too ?. First i am not sure is it really down.
Can you do your GH cycle the one you mention in your last post to see where i stand.
My Glucose level and AIc is also fine , so do i need some more test to be sure. Please help me i am loosing hope day by day, please help me sort out course of action which i can discuss with doctor as it seems like doctors are not taking it very seriously.
Rohit,
Your statement about "doctors not taking it seriously" seemed to strike a chord.
Wanted to only chime in and say.. keep the faith and don't let that add more anxiety..
The fact there are so many of us here on this board is evidence to the feeling of isolation so many of us have felt wrt the doctors.
Keep trying and pursuing more doctors and better ones.
It has taken me over 1 year to get used to the fact that NO DOCTOR "cares" about my health and to not let that hurt me. They are just not competent enough so don't take it personally....
My doctor wants to start HCG or clomid , HCG 2500IU for 3 days in a week or clomid 12.5mg /day. Can anyone suggest which one will have better results and give result faster. He thinks we need jump start leydig cells in my testes as seems like an issue with Hpothylmus /pituitary which are not sending pulse signals.. Which probably called GnRH..
Please share your stories of both clomid and HCG..
mkgbrook, please reply and others also reply .
My estrogen is 39
Tota testosterone is 211
which seems to me 1:6 ratio of estrogen to testosterone , is this look normal ?. I read it should be less then 25 and maintain 1:20 ratio . that means my testosterone has to go up for about 250 points and lower my estrogen to 25 . Should i take zinic 50mg /day along with HCG and clomid.
Clomid my doctor prescribed 12.5mg/day
for HCG my another doctor wants to add
2500IU for 3 days /week for 6 weeks . Which for me look higher and make me desensitize . Have any one used clomid and HCG together ?
You can not look at pure numbers and compare with estrogen and testosterone. You have to look at where you are in range first and then compare. Your testosterone was subnormal versus your estrogen was in normal range correct. Thus you should have more estrogen to testosterone.. which is off for a man.
Let me hit my FDA prescription database on the Clomid/HCG facts. I have been off line doing the clean and fix my house to sell it walk. Sorry for the delayed response.
Okay I am thinking that the Clomid may be better for you. Just a gut feeling. What did the MD recommend first to you? Clomid is going to work on more than one level for you. Clomid is also known as Clomiphene citrate. I think it will help you because it is capable of interacting with estrogen-receptor-containing tissues in such a way as to block some of the estrogen transport and receptor cites and reduce over all estrogen levels in addition it will interact with the hypothalamus, pituitary, ovary, endometrium, vagina, and cervix. The keys points of interaction for you are the hypothalamus and pituitary.. the others are a girl thing.
Since it has been proven to compete with estrogen for estrogen-receptor-binding sites and delay replenishment of intracellular estrogen receptors, this should help fight the lower testosterone issues by dialing back the estrogen. In addition Clomid should initiate a series of endocrine events/cycles that end in a preovulatory gonadotropin surge.. this should increase your testosterone if all works out well. The first endocrine event in response experienced is an increase in the release of pituitary gonadotropins. These are what you need.
Now HCG is used predominantly to cause ovulation in women. It can cause an increased sperm count in men. HCG has also been used in young boys when their testicles have not dropped down into the scrotum normally. This can be caused by a pituitary gland disorder. Now the HCG will not trigger as much activity in the pituitary/hypothalamus loop. It kinda bypasses it. If I were in your shoes I would go for the clomid first to see if my hypothalamus/pituitary glands can function given adequate stimuli from Clomid. If there is not significant change then I would look into HCG replacement therapy as well. I am an avid advocate of only adding one medication at a time so I can see how it effects my body. Adding the zinc and clomid together should be fine, but I would give it some time before taking on the HCG.
MG
__________________
If we learn by our mistakes, I am working on one hell of an education.
Thanks for your response and good luck in getting good price of your house.
I was thinking about adding HCG 250mcg 3 times /week along with 12.5mg clomid , i think HCG simulate testes also which will help leydig cell to start to function. As i believe 12.5mg , isn't not too low to see result ?
Should i be adding Zinic with clomid ?., is clomid already do estrogen receptor work as you said then zinic is not required to add , what do you think ?
Are you taking a multivitamin? If you are and that vitamin has chelated zinc in it.. you don't need to add zinc to your regime. If however you have no other source of zinc beyond food intake adding some shouldn't hurt you short term.
The zinc might help boost the effects and abilities of the Clomid. You are dealing with a different situation than the main one that Clomid has been tested and evaluated for. On average for a woman who doesn't ovulate they recommend a dosage of 50 milligrams (1 tablet) daily for 5 days. This should force an ovulation. From personal experience.. it does and it HURTS! Now you are in need of some hormone regulating and steady leveling. 12.5 mgs may be just fine. If not the MD may boost you to 25 mg after you get your levels rechecked. You should see some improvement with the 12.5mg.. HOW MUCH? I can not say or speculate on. The HCG may be needed alongside the clomid to get the desired effects needed. You probably should trust your MD on this one and go for it. Worse comes to worse you back off on the meds after a level recheck. I hope this is just what your body needs and you get some relief soon.
MG
__________________
If we learn by our mistakes, I am working on one hell of an education.
Yes i am taking multi vitamin which include 9mg of Zinic as well . I am not sure you know men or responded to people or read symptoms of low testosterone in men , If you can share that probably give me some ease. and less anxiety. My symptoms
Low energy
Lack concentration in work
Lack of sleep
Muscles and joint pain
muscles weakness
Low sex
low libido
Less morning errection
i was just diagnosed with pitutary cyst not sure difference tumor or cyst.... i have osteopenis hight cortisol low testorone.... iam sure all linked to cyst i see a specialist on march 30......
I also have a similar problem with a partially empty sella and low testosterone. Right now I'm on TRT but I want to get off because of infertility side effects and try other treatments. How are you doing, Rohit? Have you had success with clomid or HCG to treat your low testosterone?
Well HCG surely brought up my testosterone level, but i am worried if that desentize my leydig cells , so my doctor started clomid 50mg /day to bring up my LH and FSH as those were way down below low level. I am taking clomid for last few weeks , it surely increased my LH to 5.5 from 0.2 and FSH to 1.4 from 0.2 but my testosterone went down from 500 to 309. My testes size surely increased however my testosterone didn't go up , so i am thinking i may be permantly damaged my leydig cell .
I am looking for some ideas to jump start my testes without desensitze my leydig cells. Should i start HCG again and this time small dose like 200IU /day or 100IU /day to see in period of few weeks it starts ?.
I still think all my issues were thyroid related , no doctor since i started corrected it ,
My TSH is 1.56
FT4 1.31
FT3 3.1
My FT4 and FT3 should be above 1.7 and 4.0 to feel good . My doctor started cytomel of 10mcg /day but instead it increase my level it dropped down from 3.8 to 3.1 .. may be because i didn't wait enough to do test.
what do you guys say , if thyroid is not optimal those low testosterone can be reason?
ALWAYS get a second opinion.
