Question about injectables and PCOS - Polycystic Ovary Syndrome (PCOS) Message Board

Vino · 07-29-2003, 04:32 PM

If PCOSers are set up naturally to overstimulate with gonadotropins, then why would a dr. put someone with PCOS on a higher dose than one would normally start at?
Most people start on 75 ml, while my dr. is starting me on 112.5 mls. I am just so scared that this cycle will fail for producing too many follies we just can't afford it financially.

Anyhow, any advice would be great.

Thanks
Rose

adkins · 07-29-2003, 04:42 PM

I am not sure how to answer your question about WHY doctors put women with PCOS on injectibles. However, I do know that women with PCOS who do injectibles have been very successful.
Unfortunately for me, I did injectibles (75ml) and I DID NOT overstimulate, However, I did not get pregnant either. So, I guess I was just unlucky on my first try at getting pregnant. But was pleased my cycle was not cancelled. Our insurance did not cover it, either. It is really difficult that is why we have taken a 2- month break. If I don't get pregnant by September, then I will do injectibles again.
I hope this helps and good luck. Remember that while on injectibles, they monitor you VERY closely and can adjust your dosage along the way.
Good luck to you!!!!
Pam

suki222 · 07-29-2003, 06:27 PM

I wish I had known as much as you do. I would talk to my dr. if I were you to be sure. My dr. put me on 150 of repronex and i produced 18 mature follies and went close to hyperstimulation. We had to cancel my cycle and we were out the $ we spent on the injectibles. Over $1000. Plus all of those shots in my rear were for nothing. I'd definitely double check with him. My dr explained (AFTER I had 18 mature follies) that this happens with PCOS patients, that we stimulate easy. Well why didn't they think about that in the first place? And what about all of those u/s and lab work? I was pretty upset at having to cancel that cycle. For this cycle, though, he cut the dose in half and then upped it a little half way through. I only had two mature follies. I go for the blood test on Monday. If it's a BFN I'm going to make sure I talk to the dr more and tell him my concerns as they come up. Injectibles are expensive. I hope this helps.

Good luck!

Vino · 07-29-2003, 07:56 PM

Thanks Suki and Adkins for your reply.
I feel that being informed is empowering. It sorta gives me a false sense of control. LOL!!!

Anyhow, I realize that they do monitor you closely, and I go back on day 9 which is Saturday. I hope that everything will be alright.

Thanks again,
Rose

Gr8fuldead69 · 07-29-2003, 10:29 PM

OMG, 18 follicles

I have PCOS and I've done four cycles with injectibles (follistim). They had my dosage up to 4 amps (300 UI) daily. One cycle I had 2 follicles, the other 3 I only had one.

Just make sure they have you going in for u/s every couple days so they can adjust the dosage if necessary. Good luck!!

~ Joelle