I'm a 68 year old female and I was diagnosed with Pyoderma Gangrenosum a year and half ago(May of 2007) When I first got the spot on my leg my doctor said it was a brown recluse spider bite...After weeks it grew larger and larger, I was sent to a Plastic Surgeon. He started debriding the wound, which only made it larger. He sent me to an infectious disease doctor. After taking several antibotics and not getting any better, he sent me to a dermatologist. After 3 months of going from doctor to doctor, I was correctly diagnosed with PG. The dermatologist immediately put me on very large doses of Prednisone and Dapsone. Both these drugs caused many side affects (couldn't sleep, very nervous, tremendous uncontrollable weight gain as well as others). After several months the dosage was dropped . I continued on both drugs for months and finally was almost completely healed. I started walking to try and lose some of the weight and my leg became very swollen and caused another breakout. Now the second leison is as large as the first one. I read about a treatment on the Internet called IVIG (intravenous immune gobulin). I asked my doctors about this treatment and none of them knew anything about using this treatment for PG. Finally, I found a doctor who would administer the IV drug (which is really really very expensive, and I don't know if Medicare will pay). I have had three five day treatments over the past three months and it does not seem to be working. I go to a wound care center and they have tried different bandages, artifical skin,, etc. but nothing is working. My Dermatologist is sending me to a teaching hospital in our State to see a specialist and hopefully I will receive some type of treatment that will help me. I have had this disease for over a year and half, dealt with tremendous pain, side affects from the different medications, doing my own dressings every other day and just trying to survive. I've givien up doing simple things because the pain and meds will not allow me or give me the energy to complete simple tasks. I have always been a dancer, but NO MORE. I've always been very active, but NO MORE...I've always been an optimistic person, very upbeat, but the depression is setting in and I am trying very hard to deal with that right now. If anyone knows of a treatment that works, or something that will help, please please let me know. Also, I have been tested for the systemic disases that can cause PG, but the doctors have found nothing...Guess I'm one of the 100,000 in one who gets this disease for no reason. If you have any thoughts or questions, please reply to me and I will answer your questons best I can.
Last edited by rendam1; 12-11-2008 at 08:22 AM.