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Old 01-09-2005, 09:52 PM   #1
Join Date: Jan 2005
Posts: 1
JHL04 HB User
Medications that cause RLS?

Can anyone tell me what medications can cause RLS? I was in the hospital a few weeks ago and was given Phenergan. About 8-10 minutes later I had what was perhaps the worse episode of RLS I've ever had. Are there any other medications (especially over-the-counter medications) that can cause RLS?

Any help would be appreciated.

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Old 01-10-2005, 02:56 AM   #2
Join Date: Jun 2003
Location: a sink hole in Missouri
Posts: 98
Newsome HB User
Re: Medications that cause RLS?

Antihistamines like in Tylenol PM, Sominex, etc.

Old 01-10-2005, 10:22 AM   #3
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Join Date: Dec 2004
Location: tx
Posts: 30
rlslifer HB User
Re: Medications that cause RLS?

For a complete list, try Southern Californa Restless Leg Sipport Group.
They offer a ******** card to alert medical personel about your condition and the possible side effects of commonly use medication.
Here's a good portion of the growing list of medications that RLSers should avoid.

ANTI-NAUSEATES: Benadryl, Antivert, Atarax, Bonine, Compazine, Phenergan, thorazine, Tigan, Trilaton, Vistaril, Reglan. Suggested alternatives: Kytril, Sofran

Haldol, Loxitane, Mellaril, Motan, Navane, Prolixin, Risperdal, Serentil, Stelazine, Thorazine, Vesperin

all can cause worsening of RLS with the possible exception of
Remeron, Serzone and Wellbutrin

Benadryl and OTC/Rx combination cold/sinus/cough medications:
Actifed, Comtrex, Contact, DimeTapp, Triaminic, Theraflu, Vicks cough syrup, Tylenol PM, Exedrin PM, Bayer PM.

Hope this helps.

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