I was given Mirapex about a year ago and I thought it was a miracle drug! I hadn't been able to sleep because of Restless Leg Syndrome, Mirapex stopped the RLS and I was sleeping like a baby. However, just recently the Mirapex hadn't been working, I think I had built up a tolerance to it, seems that I do that quite quickly with most meds, I have to switch around a lot. Anyway, my doctor just started me on Neurotin instead of the Mirapex. He started me at 300 mg a day (at bedtime) it didn't help, so we increased to 600 and that has helped. I usually take the first pill an hour or so before I go to bed, then try and sit still and watch some tv to unwind, then when I'm ready to go to bed, I take the 2nd pill along with some tylenol pm and I am sleeping like a baby again. Good Luck to you.