David,
you need to find out if your sinus conditions are due to a blockage or physical defect of some kind (devaited septum, bone spur, etc.) If this is the case, surgery may be the only option of clearing up the problem. Antibiotics will not work if there is a physical problem.
Augmentin works well. Worst case scenario would include Vancomycin.
I would not under any circumstances take a quinolone or floroquinolone antibiotic (Floxin, Avelox, Levaquin, Cipro). I suffered potentially permanent nerve damage and chronic tendinitis from these. The pain I suffered from this drug made the sinus problems seem like a minor cold. There is no treatment for an adverse reaction to a quinolone. The average person takes 6 months to one year to recover completely. Most end up on disability.
These drugs are so new, the doctors don't even know exactly how they work.
The most important thing is to irrigate as much as you can (using a machine).
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